Literature DB >> 25256067

Impact of a clinical decision support system for high-alert medications on the prevention of prescription errors.

JaeHo Lee1, Hyewon Han2, Minsu Ock3, Sang-il Lee3, SunGyo Lee4, Min-Woo Jo5.   

Abstract

OBJECTIVE: To evaluate the impact of a high-alert medication clinical decision support system called HARMLESS on point-of-order entry errors in a tertiary hospital.
METHOD: HARMLESS was designed to provide three kinds of interventions for five high-alert medications: clinical knowledge support, pop-ups for erroneous orders that block the order or provide a warning, and order recommendations. The impact of this program on prescription order was evaluated by comparing the orders in 6 month periods before and after implementing the program, by analyzing the intervention log data, and by checking for order pattern changes. RESULT: During the entire evaluation period, there were 357,417 orders and 5233 logs. After HARMLESS deployment, orders that omitted dilution fluids and exceeded the maximum dose dropped from 12,878 and 214 cases to 0 and 9 cases, respectively. The latter nine cases were unexpected, but after the responsible programming error was corrected, there were no further such cases. If all blocking interventions were seen as errors that were prevented, this meant that 4137 errors (3584 of which were 'dilution fluid omitted' errors) were prevented over the 6-month post-deployment period. There were some unexpected order pattern changes after deployment and several unexpected errors emerged, including intramuscular or intravenous push orders for potassium chloride (although a case review revealed that the drug was not actually administered via these methods) and an increase in pro re nata (PRN; administer when required) orders for most drugs.
CONCLUSION: HARMLESS effectively implemented blocking interventions but was associated with the emergence of unexpected errors. After a program is deployed, it must be monitored and subjected to data analysis to fix bugs and prevent the emergence of new error types.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Clinical decision support systems; Computerized physician order entry system; Medication errors; Patient safety

Mesh:

Year:  2014        PMID: 25256067     DOI: 10.1016/j.ijmedinf.2014.08.006

Source DB:  PubMed          Journal:  Int J Med Inform        ISSN: 1386-5056            Impact factor:   4.046


  7 in total

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Authors:  J Bouaud; V Koutkias
Journal:  Yearb Med Inform       Date:  2015-08-13

2.  Differences, Opportunities, and Strategies in Drug Alert Optimization-Experiences of Two Different Integrated Health Care Systems.

Authors:  Salim M Saiyed; Katherine R Davis; David C Kaelber
Journal:  Appl Clin Inform       Date:  2019-10-16       Impact factor: 2.342

3.  Designing Interactive Alerts to Improve Recognition of Critical Events in Medical Emergencies.

Authors:  Angela Mastrianni; Aleksandra Sarcevic; Lauren S Chung; Issa Zakeri; Emily C Alberto; Zachary P Milestone; Randall S Burd; Ivan Marsic
Journal:  DIS (Des Interact Syst Conf)       Date:  2021-06-28

4.  Cost-effectiveness of an electronic clinical decision support system for improving quality of antenatal and childbirth care in rural Tanzania: an intervention study.

Authors:  Happiness Pius Saronga; Els Duysburgh; Siriel Massawe; Maxwell Ayindenaba Dalaba; Peter Wangwe; Felix Sukums; Melkizedeck Leshabari; Antje Blank; Rainer Sauerborn; Svetla Loukanova
Journal:  BMC Health Serv Res       Date:  2017-08-07       Impact factor: 2.655

Review 5.  Systematic Review of Medical Informatics-Supported Medication Decision Making.

Authors:  Brittany L Melton
Journal:  Biomed Inform Insights       Date:  2017-03-30

6.  Detection of overdose and underdose prescriptions-An unsupervised machine learning approach.

Authors:  Kenichiro Nagata; Toshikazu Tsuji; Kimitaka Suetsugu; Kayoko Muraoka; Hiroyuki Watanabe; Akiko Kanaya; Nobuaki Egashira; Ichiro Ieiri
Journal:  PLoS One       Date:  2021-11-19       Impact factor: 3.240

7.  High alert drugs screening using gradient boosting classifier.

Authors:  Pakpoom Wongyikul; Nuttamon Thongyot; Pannika Tantrakoolcharoen; Pusit Seephueng; Piyapong Khumrin
Journal:  Sci Rep       Date:  2021-10-11       Impact factor: 4.379

  7 in total

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