Mona Gangar1, John P Bent. 1. Children's Hospital at Montefiore, Montefiore Medical Center, Bronx, New York, New York, USA.
Abstract
PURPOSE OF REVIEW: To describe the efficacy of mitomycin C in combating airway stenosis. RECENT FINDINGS: Recent publications discussing mitomycin C utility have not altered the mixed results previously established by prospective trials. SUMMARY: Mitomycin C has been used for the past 16 years to inhibit pediatric airway fibroblast proliferation. Its benefit remains more hypothetical than proven and its future role remains uncertain.
PURPOSE OF REVIEW: To describe the efficacy of mitomycin C in combating airway stenosis. RECENT FINDINGS: Recent publications discussing mitomycin C utility have not altered the mixed results previously established by prospective trials. SUMMARY:Mitomycin C has been used for the past 16 years to inhibit pediatric airway fibroblast proliferation. Its benefit remains more hypothetical than proven and its future role remains uncertain.