Literature DB >> 25254155

Neurophysiology and Clinical Implications of the Laryngeal Adductor Reflex.

Amanda S Domer1, Maggie A Kuhn2, Peter C Belafsky3.   

Abstract

The laryngeal adductor reflex (LAR) is an involuntary protective response to stimuli in the larynx. The superior laryngeal nerve (SLN) acts as the afferent limb and the recurrent laryngeal nerve (RLN) as the efferent limb of this reflex, which is modulated by the central nervous system. Perhaps the most clinically significant application of the LAR is its use in laryngopharyngeal (LP) sensory discrimination testing. Importantly, aberrations in the LAR may predict dysphagia or portend clinical phenotypes of chronic cough, vocal cord dysfunction or pediatric apneas. LP sensation is a potential target for interventions addressing the aforementioned conditions though currently remains an area of active investigation.

Entities:  

Keywords:  LAR; glottic closure reflex; laryngeal sensory testing; laryngopharyngeal sensation; superior laryngeal nerve

Year:  2013        PMID: 25254155      PMCID: PMC4171040          DOI: 10.1007/s40136-013-0018-5

Source DB:  PubMed          Journal:  Curr Otorhinolaryngol Rep


  43 in total

1.  A new noninvasive method for determination of laryngeal sensory function.

Authors:  Jonathan M Bock; Joel H Blumin; Robert J Toohill; Albert L Merati; Thomas E Prieto; Safwan S Jaradeh
Journal:  Laryngoscope       Date:  2011-01       Impact factor: 3.325

2.  Effects of altered consciousness on the protective glottic closure reflex.

Authors:  Clarence T Sasaki; Ziwei Yu; Jiajun Xu; Jagdeep Hundal; William Rosenblatt
Journal:  Ann Otol Rhinol Laryngol       Date:  2006-10       Impact factor: 1.547

3.  The effect of tracheostomy on the laryngeal closure reflex.

Authors:  C T Sasaki; M Suzuki; M Horiuchi; J A Kirchner
Journal:  Laryngoscope       Date:  1977-09       Impact factor: 3.325

4.  Laryngeal and velopharyngeal sensory impairment in obstructive sleep apnea.

Authors:  Anh Tu Duy Nguyen; Vincent Jobin; Richard Payne; Josée Beauregard; Naftaly Naor; R John Kimoff
Journal:  Sleep       Date:  2005-05       Impact factor: 5.849

5.  The effect of chronic obstructive pulmonary disease on laryngopharyngeal sensitivity.

Authors:  Nicola A Clayton; Giselle D Carnaby-Mann; Matthew J Peters; Alvin J Ing
Journal:  Ear Nose Throat J       Date:  2012-09       Impact factor: 1.697

6.  Laryngeal sensory deficits in patients with chronic cough and paradoxical vocal fold movement disorder.

Authors:  Thomas Murry; Ryan C Branski; Kathy Yu; Sabrina Cukier-Blaj; Suzy Duflo; Jonathan E Aviv
Journal:  Laryngoscope       Date:  2010-08       Impact factor: 3.325

7.  Altered laryngeal sensation: a potential cause of apnea of infancy.

Authors:  Dana M Thompson; Michael J Rutter; Colin D Rudolph; J Paul Willging; Robin T Cotton
Journal:  Ann Otol Rhinol Laryngol       Date:  2005-04       Impact factor: 1.547

8.  In-office evaluation of swallowing: FEES, pharyngeal squeeze maneuver, and FEESST.

Authors:  Albert L Merati
Journal:  Otolaryngol Clin North Am       Date:  2013-02       Impact factor: 3.346

Review 9.  Cough and the common cold: ACCP evidence-based clinical practice guidelines.

Authors:  Melvin R Pratter
Journal:  Chest       Date:  2006-01       Impact factor: 9.410

10.  A cohort description and analysis of the effect of gabapentin on idiopathic cough.

Authors:  Charlotte Van de Kerkhove; Pieter C Goeminne; Pascal Van Bleyenbergh; Lieven J Dupont
Journal:  Cough       Date:  2012-11-01
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  5 in total

1.  Changes in Peak Airflow Measurement During Maximal Cough After Vocal Fold Augmentation in Patients With Glottic Insufficiency.

Authors:  Gregory R Dion; Efstratios Achlatis; Stephanie Teng; Yixin Fang; Michael Persky; Ryan C Branski; Milan R Amin
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2017-11-01       Impact factor: 6.223

2.  The functional role of the pharyngeal plexus in vocal cord innervation in humans.

Authors:  Mehmet Uludag; Nurcihan Aygun; Adnan Isgor
Journal:  Eur Arch Otorhinolaryngol       Date:  2016-11-03       Impact factor: 2.503

3.  Relationship Between Laryngeal Sensation, Length of Intubation, and Aspiration in Patients with Acute Respiratory Failure.

Authors:  James C Borders; Daniel Fink; Joseph E Levitt; Jeffrey McKeehan; Edel McNally; Alix Rubio; Rebecca Scheel; Jonathan M Siner; Stephanie Gomez Taborda; Rosemary Vojnik; Heather Warner; S David White; Susan E Langmore; Marc Moss; Gintas P Krisciunas
Journal:  Dysphagia       Date:  2019-01-29       Impact factor: 3.438

4.  Advancing Laryngeal Adductor Reflex Testing Beyond Sensory Threshold Detection.

Authors:  Teresa E Lever; Ashley M Kloepper; Ian Deninger; Ali Hamad; Bridget L Hopewell; Alyssa K Ovaitt; Marlena Szewczyk; Filiz Bunyak; Bradford Zitsch; Brett Blake; Caitlin Vandell; Laura Dooley
Journal:  Dysphagia       Date:  2021-10-22       Impact factor: 2.733

5.  Relationship Between Laryngeal Sensory Deficits, Aspiration, and Pneumonia in Patients with Dysphagia.

Authors:  Asako Kaneoka; Jessica M Pisegna; Haruhi Inokuchi; Rumi Ueha; Takao Goto; Takaharu Nito; Cara E Stepp; Michael P LaValley; Nobuhiko Haga; Susan E Langmore
Journal:  Dysphagia       Date:  2017-09-02       Impact factor: 3.438

  5 in total

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