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Literature DB >> 25253941

Immune reaction and colorectal cancer: friends or foes?

Vincenzo Formica¹, Vittore Cereda¹, Antonella Nardecchia¹, Manfredi Tesauro¹, Mario Roselli¹.

Abstract

The potential clinical impact of enhancing antitumor immunity is increasingly recognized in oncology therapeutics for solid tumors. Colorectal cancer is one of the most studied neoplasms for the tumor-host immunity relationship. Although immune cell populations involved in such a relationship and their prognostic role in colorectal cancer development have clearly been identified, still no approved therapies based on host immunity intensification have so far been introduced in clinical practice. Moreover, a recognized risk in enhancing immune reaction for colitis-associated colorectal cancer development has limited the emphasis of this approach. The aim of the present review is to discuss immune components involved in the host immune reaction against colorectal cancer and analyze the fine balance between pro-tumoral and anti-tumoral effect of immunity in this model of disease.

Entities: Disease

Keywords: Adaptive immunity; Antitumor immunity; Colitis-associated colorectal cancer; Innate immunity

Mesh：

Substances：
Inflammation Mediators

Year: 2014 PMID： 25253941 PMCID： PMC4168074 DOI： 10.3748/wjg.v20.i35.12407

Source DB: PubMed Journal: World J Gastroenterol ISSN： 1007-9327 Impact factor: 5.742

103 in total

Review 1. Inflammatory bowel disease.

Authors: Daniel K Podolsky
Journal: N Engl J Med Date: 2002-08-08 Impact factor: 91.245

2. Effector memory T cells, early metastasis, and survival in colorectal cancer.

Authors: Franck Pagès; Anne Berger; Matthieu Camus; Fatima Sanchez-Cabo; Anne Costes; Robert Molidor; Bernhard Mlecnik; Amos Kirilovsky; Malin Nilsson; Diane Damotte; Tchao Meatchi; Patrick Bruneval; Paul-Henri Cugnenc; Zlatko Trajanoski; Wolf-Herman Fridman; Jérôme Galon
Journal: N Engl J Med Date: 2005-12-22 Impact factor: 91.245

3. Enterococcal endocarditis associated with carcinoma of the sigmoid; report of a case.

Authors: W C McCOY; J M MASON
Journal: J Med Assoc State Ala Date: 1951-12

4. Understanding the IL-23-IL-17 immune pathway.

Authors: Brent S McKenzie; Robert A Kastelein; Daniel J Cua
Journal: Trends Immunol Date: 2005-11-14 Impact factor: 16.687

5. The risk of colorectal cancer in ulcerative colitis: a meta-analysis.

Authors: J A Eaden; K R Abrams; J F Mayberry
Journal: Gut Date: 2001-04 Impact factor: 23.059

Review 6. Interleukin-18 and the pathogenesis of inflammatory diseases.

Authors: Charles A Dinarello
Journal: Semin Nephrol Date: 2007-01 Impact factor: 5.299

7. MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis.

Authors: Akihiro Araki; Takanori Kanai; Takahiro Ishikura; Shin Makita; Koji Uraushihara; Ryoichi Iiyama; Teruji Totsuka; Kiyoshi Takeda; Shizuo Akira; Mamoru Watanabe
Journal: J Gastroenterol Date: 2005-01 Impact factor: 7.527

Review 8. The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment.

Authors: Alexander Greenhough; Helena J M Smartt; Amy E Moore; Heather R Roberts; Ann C Williams; Christos Paraskeva; Abderrahmane Kaidi
Journal: Carcinogenesis Date: 2009-01-09 Impact factor: 4.944

9. Carcinogenic properties of proteins with pro-inflammatory activity from Streptococcus infantarius (formerly S.bovis).

Authors: Jordane Biarc; Isabelle S Nguyen; Annelise Pini; Francine Gossé; Sophie Richert; Danielle Thiersé; Alain Van Dorsselaer; Emmanuelle Leize-Wagner; Francis Raul; Jean-Paul Klein; Marie Schöller-Guinard
Journal: Carcinogenesis Date: 2004-01-23 Impact factor: 4.944

10. NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens.

Authors: Paras K Anand; R K Subbarao Malireddi; John R Lukens; Peter Vogel; John Bertin; Mohamed Lamkanfi; Thirumala-Devi Kanneganti
Journal: Nature Date: 2012-08-16 Impact factor: 49.962

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Review 1. Targeted therapy in first line treatment of RAS wild type colorectal cancer.

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Journal: World J Gastroenterol Date: 2015-03-14 Impact factor: 5.742

2. Mechanistic roles of epithelial and immune cell signaling during the development of colitis-associated cancer.

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Journal: Cancer Res Front Date: 2016-01-21

3. Systemic and local inflammation in colorectal cancer.

Authors: Roberts Rumba; Sandra Cipkina; Fanija Cukure; Andrejs Vanags
Journal: Acta Med Litu Date: 2018

Review 4. From inflammatory bowel disease to colorectal cancer: what's the role of miRNAs?

Authors: Mostafa Vaghari-Tabari; Niloufar Targhazeh; Soheila Moein; Durdi Qujeq; Forough Alemi; Maryam Majidina; Simin Younesi; Zatollah Asemi; Bahman Yousefi
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5. Chemopreventive effects of Ku-jin tea against AOM-induced precancerous colorectal lesions in rats and metabolomic analysis.

Authors: Wu Bi; Haibo Liu; Jie Shen; Ling-Hua Zhang; Pei Li; Bing Peng; Li Cao; Pengfei Zhang; Chunnian He; Peigen Xiao
Journal: Sci Rep Date: 2017-11-21 Impact factor: 4.379