Literature DB >> 25253938

Extrahepatic immune related manifestations in chronic hepatitis C virus infection.

Maria Tampaki1, John Koskinas1.   

Abstract

The association of chronic hepatitis C with immune related syndromes has been frequently reported. There is a great range of clinical manifestations affecting various systems and organs such as the skin, the kidneys, the central and peripheral nervous system, the musculoskeletal system and the endocrine glands. Despite the high prevalence of immune related syndromes in patients with chronic hepatitis C, the exact pathogenesis is not always clear. They have been often associated with mixed cryoglobulinemia, a common finding in chronic hepatitis C, cross reaction with viral antigens, or the direct effect of virus on the affected tissues. The aim of this review is to analyze the reported hepatitis C virus immune mediated syndromes, their prevalence and clinical manifestations and to discuss the most supported theories regarding their pathogenesis.

Entities:  

Keywords:  Autoimmune; Cryoglobulinemia; Extrahepatic manifestations; Hepatitis C virus

Mesh:

Year:  2014        PMID: 25253938      PMCID: PMC4168071          DOI: 10.3748/wjg.v20.i35.12372

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  68 in total

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Journal:  Exp Dermatol       Date:  1999-12       Impact factor: 3.960

2.  Serum autoantibodies positivity prevalence in patients with chronic HCV and impact on pegylated interferon and ribavirin treatment response.

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Journal:  Liver Int       Date:  2013-06-14       Impact factor: 5.828

3.  Immunohistochemical detection of HCV in nerves and muscles of patients with HCV associated peripheral neuropathy and myositis.

Authors:  Layla K Younis; Farouk M Talaat; Ahmed H Deif; Mohamed F Borei; Seham M Abdel Reheim; Doa H El Salmawy
Journal:  Int J Health Sci (Qassim)       Date:  2007-07

4.  Presence of hepatitis C virus RNA in the salivary glands of patients with Sjögren's syndrome and hepatitis C virus infection.

Authors:  Eric Toussirot; Gaëlle Le Huédé; Christiane Mougin; Jean-Charles Balblanc; Dominique Bettinger; Daniel Wendling
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Review 5.  Hepatitis C virus, cryoglobulinaemia, and vasculitis: immune complex relations.

Authors:  Domenico Sansonno; Franco Dammacco
Journal:  Lancet Infect Dis       Date:  2005-04       Impact factor: 25.071

6.  Similar serum levels of IL-6 and its soluble receptors in patients with HCV-related arthritis and rheumatoid arthritis: a pilot study.

Authors:  A Riccio; L Postiglione; P Sabatini; M Linvelli; I Soriente; M G Sangiolo; P Amato; G Tarantino
Journal:  Int J Immunopathol Pharmacol       Date:  2012 Jan-Mar       Impact factor: 3.219

7.  Severe hepatitis C virus-related cryoglobulinaemic sensory-motor polyneuropathy treated with pegylated interferon-a2b and ribavirin: clinical, laboratory and neurophysiological study.

Authors:  J Koskinas; C Kilidireas; N Karandreas; D Kountouras; S Savvas; E Hadziyannis; A J Archimandritis
Journal:  Liver Int       Date:  2007-04       Impact factor: 5.828

8.  Chronic lymphocytic sialoadenitis in HCV-related chronic liver disease: comparison of Sjögren's syndrome.

Authors:  C A Scott; C Avellini; L Desinan; M Pirisi; G F Ferraccioli; P Bardus; C Fabris; L Casatta; E Bartoli; C A Beltrami
Journal:  Histopathology       Date:  1997-01       Impact factor: 5.087

9.  Systemic autoimmune diseases in patients with hepatitis C virus infection: characterization of 1020 cases (The HISPAMEC Registry).

Authors:  Manuel Ramos-Casals; Sandra Muñoz; Francisco Medina; Luis-Javier Jara; José Rosas; Jaime Calvo-Alen; Pilar Brito-Zerón; Xavier Forns; Jose-Maria Sánchez-Tapias
Journal:  J Rheumatol       Date:  2009-04-15       Impact factor: 4.666

10.  Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: possible role for molecular mimicry.

Authors:  Salvatore Sutti; Matteo Vidali; Cristina Mombello; Massimo Sartori; Magnus Ingelman-Sundberg; Emanuele Albano
Journal:  J Hepatol       Date:  2010-05-31       Impact factor: 25.083

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  5 in total

Review 1.  Epidemiology of hepatitis C virus in Iran.

Authors:  Reza Taherkhani; Fatemeh Farshadpour
Journal:  World J Gastroenterol       Date:  2015-10-14       Impact factor: 5.742

2.  Efficacy and safety of Glecaprevir/Pibrentasvir in the treatment of mixed cryo-globulinemia due to chronic hepatitis C cirrhosis in a patient with chronic kidney disease.

Authors:  N Papadopoulos; S Flouda; E Sveroni; M C Tatarida Palla; V German
Journal:  Hippokratia       Date:  2019 Jan-Mar       Impact factor: 0.471

Review 3.  Rheumatic manifestations of hepatitis C virus chronic infection: Indications for a correct diagnosis.

Authors:  Carlo Palazzi; Emilio D'Amico; Salvatore D'Angelo; Michele Gilio; Ignazio Olivieri
Journal:  World J Gastroenterol       Date:  2016-01-28       Impact factor: 5.742

4.  Orbital Pseudotumor as a Rare Extrahepatic Manifestation of Hepatitis C Infection.

Authors:  Benjamin Misselwitz; Jana Epprecht; Joachim Mertens; Luc Biedermann; Michael Scharl; Eugenia Haralambieva; Andreas Lutterotti; Konrad P Weber; Beat Müllhaupt; Karla Chaloupka
Journal:  Case Rep Gastroenterol       Date:  2016-05-19

Review 5.  Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms.

Authors:  Maria K Smatti; Farhan S Cyprian; Gheyath K Nasrallah; Asmaa A Al Thani; Ruba O Almishal; Hadi M Yassine
Journal:  Viruses       Date:  2019-08-19       Impact factor: 5.048

  5 in total

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