Literature DB >> 25253936

Tobacco dust, genotoxicity, and bidi-making cottage industry.

Sim Sai Tin1, Viroj Wiwanitkit2.   

Abstract

Entities:  

Year:  2014        PMID: 25253936      PMCID: PMC4170568          DOI: 10.4103/0971-6580.139818

Source DB:  PubMed          Journal:  Toxicol Int        ISSN: 0971-6580


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Sir, The report on “tobacco Dust induced genotoxicity as an occupational hazard in workers of bidi making cottage industry of central India” is very interesting.[1] Khanna et al. noted that “bidi rollers seem to be facing the occupational hazard of genotoxicity due to handling bidi tobacco and inhalation of tobacco dust.[1]” Indeed, this topic is not a new thing. Previously, Mahimkar and Bhisey reported that “occupational exposure to bidi tobacco increases chromosomal aberrations in tobacco processors.[2]” Mahimkar and Bhisey reported for “a significant increase in deletion fragments and chromatid gaps in the exposed group.[2]” However, based on the present report by Khanna et al.,[1] it can confirm only that there is genotoxicity; however, the relationship to exposure might not be concluded. In fact, to confirm the exposure, biomarker monitoring is required. The available biomarkers include blood and urine levels including cotinine, thioethers, etc.[34]
  4 in total

1.  Biological monitoring of bidi industry workers occupationally exposed to tobacco.

Authors:  R A Bhisey; A N Bagwe; M B Mahimkar; S C Buch
Journal:  Toxicol Lett       Date:  1999-09-05       Impact factor: 4.372

2.  Occupational exposure to bidi tobacco increases chromosomal aberrations in tobacco processors.

Authors:  M B Mahimkar; R A Bhisey
Journal:  Mutat Res       Date:  1995-04       Impact factor: 2.433

3.  Elevated urinary thioether excretion among bidi rollers exposed occupationally to processed tobacco.

Authors:  R B Govekar; R A Bhisey
Journal:  Int Arch Occup Environ Health       Date:  1992       Impact factor: 3.015

4.  Tobacco dust induced genotoxicity as an occupational hazard in workers of bidi making cottage industry of central India.

Authors:  Asha Khanna; Daya Shankar Gautam; Mamta Gokhale; Salil Kumar Jain
Journal:  Toxicol Int       Date:  2014-01
  4 in total

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