Literature DB >> 25253537

Protein-based fluorescent metal nanoclusters for small molecular drug screening.

Yong Yu1, Siu Yee New, Jianping Xie, Xiaodi Su, Yen Nee Tan.   

Abstract

A facile drug screening method based on synthesis of fluorescent gold nanoclusters inside albumin proteins loaded with small molecular drugs and comparing the relative fluorescence intensities of the resultant gold nanoclusters has been developed and successfully applied for the quantitative measurement of drug-protein binding constants.

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Year:  2014        PMID： 25253537     DOI： 10.1039/c4cc06914e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening.

Authors:  Yong Yu; Siu Yee New; Jiaxian Lin; Xiaodi Su; Yen Nee Tan
Journal:  J Vis Exp       Date:  2015-10-16       Impact factor: 1.355

Review 2.  Reduction of Tetrachloroaurate(III) Ions With Bioligands: Role of the Thiol and Amine Functional Groups on the Structure and Optical Features of Gold Nanohybrid Systems.

Authors:  Ditta Ungor; Imre Dékány; Edit Csapó
Journal:  Nanomaterials (Basel)       Date:  2019-08-29       Impact factor: 5.076

Review 3.  Emerging Strategies in Enhancing Singlet Oxygen Generation of Nano-Photosensitizers Toward Advanced Phototherapy.

Authors:  Mohammad Tavakkoli Yaraki; Bin Liu; Yen Nee Tan
Journal:  Nanomicro Lett       Date:  2022-05-05

4.  Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications.

Authors:  Jason Y C Lim; Yong Yu; Guorui Jin; Kai Li; Yi Lu; Jianping Xie; Yen Nee Tan
Journal:  Nanoscale Adv       Date:  2020-07-23
  4 in total

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