Literature DB >> 25252924

Eurifoloids A-R, structurally diverse diterpenoids from Euphorbia neriifolia.

Jin-Xin Zhao1, Cui-Ping Liu, Wei-Yan Qi, Mei-Ling Han, Ying-Shan Han, Mark A Wainberg, Jian-Min Yue.   

Abstract

Eighteen new diterpenoids, named eurifoloids A-R (1-18), including ingenane (1 and 2), abietane (3-7), isopimarane (8-12), and ent-atisane (13-18) types, along with four known analogues were isolated from Euphorbia neriifolia. Eurifoloid M (13) represents a rare class of ent-atisane-type norditerpenoid. Eurifoloids E (5) and F (6) exhibited significant anti-HIV activities, with EC50 values of 3.58 ± 0.31 (SI = 8.6) and 7.40 ± 0.94 μM (SI = 10.3), respectively.

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Year:  2014        PMID： 25252924     DOI： 10.1021/np5004752

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  4 in total

Review 1.  Ethnobotanical Uses, Phytochemistry, Toxicology, and Pharmacological Properties of Euphorbia neriifolia Linn. against Infectious Diseases: A Comprehensive Review.

Authors:  Arifa Sultana; Md Jamal Hossain; Md Ruhul Kuddus; Mohammad A Rashid; Miss Sharmin Zahan; Saikat Mitra; Arpita Roy; Safaet Alam; Md Moklesur Rahman Sarker; Isa Naina Mohamed
Journal:  Molecules       Date:  2022-07-08       Impact factor: 4.927

Review 2.  Antiviral Profiling of C-18- or C-19-Functionalized Semisynthetic Abietane Diterpenoids.

Authors:  Miguel A González-Cardenete; Damir Hamulić; Francisco J Miquel-Leal; Natalia González-Zapata; Orlando J Jimenez-Jarava; Yaneth M Brand; Laura C Restrepo-Mendez; Marlen Martinez-Gutierrez; Liliana A Betancur-Galvis; Maria L Marín
Journal:  J Nat Prod       Date:  2022-08-15       Impact factor: 4.803

3.  PKCδ/MAPKs and NF-κB Pathways are Involved in the Regulation of Ingenane-Type Diterpenoids from Euphorbia neriifolia on Macrophage Function.

Authors:  Mingyan Jiang; Yong Xue; Jianchun Li; Kairui Rao; Shili Yan; Hongmei Li; Xuanqin Chen; Rongtao Li; Dan Liu
Journal:  J Inflamm Res       Date:  2021-06-25

Review 4.  Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus.

Authors:  Bahare Salehi; Nanjangud V Anil Kumar; Bilge Şener; Mehdi Sharifi-Rad; Mehtap Kılıç; Gail B Mahady; Sanja Vlaisavljevic; Marcello Iriti; Farzad Kobarfard; William N Setzer; Seyed Abdulmajid Ayatollahi; Athar Ata; Javad Sharifi-Rad
Journal:  Int J Mol Sci       Date:  2018-05-14       Impact factor: 5.923
  4 in total

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