Literature DB >> 25252069

Facial palsy as an unusual presenting symptom associated with acute myeloid leukemia.

Kazuo Kubota1, Michio Ozeki, Tomohiro Hori, Kaori Kanda, Michinori Funato, Takahiko Asano, Toshiyuki Fukao, Naomi Kondo.   

Abstract

Extramedullary infiltration is common in acute myeloid leukemia (AML) patients. Although AML can cause neurological symptoms, especially when associated with extramedullary infiltration, a presenting manifestation of facial palsy is rare. We report on a 1-year-old boy who developed right facial palsy. Detailed examination led to a diagnosis of AML (French-American-British classification M1). Magnetic resonance imaging enhanced with gadolinium-diethylenetriamine penta-acetic acid showed abnormal enhancement of the right facial nerve, which disappeared after chemotherapy. AML should be considered as a differential diagnosis of facial palsy. Enhanced magnetic resonance imaging may be useful for diagnosing facial palsy associated with AML and for evaluating treatment outcome.
© 2014 Japan Pediatric Society.

Entities:  

Keywords:  acute myeloid leukemia; extramedullary infiltration; facial palsy; trisomy 8

Mesh:

Year:  2014        PMID: 25252069     DOI: 10.1111/ped.12384

Source DB:  PubMed          Journal:  Pediatr Int        ISSN: 1328-8067            Impact factor:   1.524


  2 in total

Review 1.  Facial paralysis as a presenting symptom of infant leukemia: A case report and literature review.

Authors:  Liyuan Wang; Zhiling Wang; Chaomin Wan; Xiaotang Cai; Ge Zhang; Chunqi Lai
Journal:  Medicine (Baltimore)       Date:  2018-12       Impact factor: 1.889

2.  Chemotherapy as Treatment for Acute Myeloid Leukemia (AML)-Induced Facial Nerve Palsy.

Authors:  Michael Fana; Brook Centofanti; Philip Kuriakose
Journal:  Cureus       Date:  2022-03-31
  2 in total

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