Literature DB >> 25251733

Systematic review of neonatal seizure management strategies provides guidance on anti-epileptic treatment.

Lena Hellström-Westas1, Geraldine Boylan, Johan Ågren.   

Abstract

UNLABELLED: There is a lack of scientific evidence to support the best management of neonatal seizures. Current strategies for neonatal seizure management were investigated by analysis of all surveys published during the time period 2000-2012. Methods for seizure diagnosis and availability of electroencephalogram (EEG), including monitoring, varied. Phenobarbital was the drug of first choice, and the use of off-label drugs and treatment times varied.
CONCLUSION: We conclude that there is an urgent need for more evidence-based studies to guide neonatal seizure management. ©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Anti-epileptic drugs; Electroencephalogram; Newborn; Phenobarbital; Status epilepticus

Mesh：

Substances：

Year:  2014        PMID： 25251733     DOI： 10.1111/apa.12812

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN： 0803-5253            Impact factor:   2.299


  14 in total

1.  Phenobarbital Treatment at a Neonatal Age Results in Decreased Efficacy of Omeprazole in Adult Mice.

Authors:  Yun-Chen Tien; Stephanie C Piekos; Chad Pope; Xiao-Bo Zhong
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2.  Time and sex dependent effects of magnesium sulphate on post-asphyxial seizures in preterm fetal sheep.

Authors:  Laura Bennet; Robert Galinsky; Vittoria Draghi; Christopher A Lear; Joanne O Davidson; Charles P Unsworth; Alistair J Gunn
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Journal:  Pediatr Res       Date:  2022-10-04       Impact factor: 3.953

4.  Rescue of PB-resistant neonatal seizures with single-dose of small-molecule TrkB antagonist show long-term benefits.

Authors:  S K Kang; S Ammanuel; D A Adler; S D Kadam
Journal:  Epilepsy Res       Date:  2019-12-09       Impact factor: 3.045

5.  Management and investigation of neonatal encephalopathy: 2017 update.

Authors:  Kathryn Martinello; Anthony R Hart; Sufin Yap; Subhabrata Mitra; Nicola J Robertson
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2017-04-06       Impact factor: 5.747

Review 6.  A Model of Perinatal Ischemic Stroke in the Rat: 20 Years Already and What Lessons?

Authors:  Christiane Charriaut-Marlangue; Olivier Baud
Journal:  Front Neurol       Date:  2018-08-07       Impact factor: 4.003

7.  Levetiracetam optimal dose-finding as first-line treatment for neonatal seizures occurring in the context of hypoxic-ischaemic encephalopathy (LEVNEONAT-1): study protocol of a phase II trial.

Authors:  Geraldine Favrais; Moreno Ursino; Catherine Mouchel; Estelle Boivin; Vincent Jullien; Sarah Zohar; Elie Saliba
Journal:  BMJ Open       Date:  2019-01-24       Impact factor: 2.692

8.  Population Pharmacokinetics of Phenobarbital in Neonates and Infants on Extracorporeal Membrane Oxygenation and the Influence of Concomitant Renal Replacement Therapy.

Authors:  Céline Thibault; Shavonne L Massey; Nicholas S Abend; Maryam Y Naim; Alexandra Zoraian; Athena F Zuppa
Journal:  J Clin Pharmacol       Date:  2020-09-22       Impact factor: 3.126

9.  Causes and Factors Associated with Neonatal Seizure and its Short-term Outcome: A Retrospective Prognostic Cohort Study.

Authors:  Hamid Nemati; Parvaneh Karimzadeh; Minoo Fallahi
Journal:  Iran J Child Neurol       Date:  2018

10.  Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures.

Authors:  Sean M M Quinlan; Natalia Rodriguez-Alvarez; Eleanor J Molloy; Stephen F Madden; Geraldine B Boylan; David C Henshall; Eva M Jimenez-Mateos
Journal:  Sci Rep       Date:  2018-07-03       Impact factor: 4.379
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