Literature DB >> 25250977

Synthesis of 2-vinylbenzofurans via the copper-catalyzed multicomponent reactions involving an oxa-Michael/arylation/vinylation cascade.

Jie-Ping Wan1, Hang Wang, Yunyun Liu, Hanfeng Ding.   

Abstract

2-Vinylbenzofurans have been synthesized via the copper-catalyzed one-pot, three-component reactions of o-iodophenols, in situ generated allenes, and dichloromethane. Cascade transformation of oxa-Michael addition, C-arylation, and sp(3)C-H/sp(3)C-Cl conversion-based vinylation has been involved in realizing the construction of this 2-vinylbenzofuran framework.

Entities:  

Year:  2014        PMID： 25250977     DOI： 10.1021/ol502506g

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

Review 1.  Last Decade of Unconventional Methodologies for the Synthesis of Substituted Benzofurans.

Authors:  Lucia Chiummiento; Rosarita D'Orsi; Maria Funicello; Paolo Lupattelli
Journal:  Molecules       Date:  2020-05-16       Impact factor: 4.411

2.  Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH2 insertion.

Authors:  Mohamed Elagawany; Lingaiah Maram; Bahaa Elgendy
Journal:  RSC Adv       Date:  2021-02-17       Impact factor: 3.361

3.  A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations.

Authors:  Xinlong Pang; Chao Chen; Ming Li; Chanjuan Xi
Journal:  Beilstein J Org Chem       Date:  2015-11-30       Impact factor: 2.883

4.  Synthesis of β-arylated alkylamides via Pd-catalyzed one-pot installation of a directing group and C(sp(3))-H arylation.

Authors:  Yunyun Liu; Yi Zhang; Xiaoji Cao; Jie-Ping Wan
Journal:  Beilstein J Org Chem       Date:  2016-06-03       Impact factor: 2.883
  4 in total

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