Gwendoline Menga1, Sharon Ing2, Omar Khan2, Bobby Dupre3, Adriana C Dornelles4, Anika Alarakhia2, William Davis5, Jerald Zakem5, Tamika Webb-Detiege5, Eve Scopelitis5, Robert Quinet5. 1. Department of Rheumatology, Ochsner Health Center-Baton Rouge, Baton Rouge, LA. 2. Department of Rheumatology, Ochsner Clinic Foundation, New Orleans, LA. 3. Primary Care of Brusly, Port Allen, LA. 4. Office of Biostatistical Support, Ochsner Clinic Foundation, New Orleans, LA. 5. Department of Rheumatology, Ochsner Clinic Foundation, New Orleans, LA ; The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA.
Abstract
BACKGROUND:Cognitive behavioral therapy (CBT) has proven useful in treating fibromyalgia, depression, and anxiety. Computerized delivery of CBT allows increased access to such therapy. This study assessed the effect of internet-based CBT on Fibromyalgia Impact Questionnaire (FIQ) composite scores and tender point assessments. METHODS: This 12-week randomized controlled trial included patients ≥18 years of age with 1990 American College of Rheumatology criteria for fibromyalgia and mild to moderate depression and anxiety. A total of 56 subjects were randomized into either a 6-week internet-based CBT group (MoodGYM) or a control group (standard care). We evaluated patients in both groups at 1-, 6-, and 12-week follow-up. The primary outcome measure was change in FIQ composite score. A secondary outcome measure was change in tender point assessment. RESULTS:The mean age of study participants was 55 years, and 88% were female. Mean FIQ scores were significantly lower in the MoodGYM group compared to the control group (P<0.05 for group differences at 6 and 12 weeks). Mean tender point scores were also significantly lower in the MoodGYM group (P<0.001 at 6 and 12 weeks). We found no significant difference in the FIQ scores across the 3 timepoints in the MoodGYM group, but tender points showed a significant negative trend from baseline to 12-week follow-up. CONCLUSION: Patients in the internet-based MoodGYM CBT program had lower FIQ and tender point scores at 6- and 12-week follow-up. Internet-based CBT could be beneficial in the treatment of mild to moderate depression and anxiety in patients with fibromyalgia by allowing increased access to CBT.
RCT Entities:
BACKGROUND: Cognitive behavioral therapy (CBT) has proven useful in treating fibromyalgia, depression, and anxiety. Computerized delivery of CBT allows increased access to such therapy. This study assessed the effect of internet-based CBT on Fibromyalgia Impact Questionnaire (FIQ) composite scores and tender point assessments. METHODS: This 12-week randomized controlled trial included patients ≥18 years of age with 1990 American College of Rheumatology criteria for fibromyalgia and mild to moderate depression and anxiety. A total of 56 subjects were randomized into either a 6-week internet-based CBT group (MoodGYM) or a control group (standard care). We evaluated patients in both groups at 1-, 6-, and 12-week follow-up. The primary outcome measure was change in FIQ composite score. A secondary outcome measure was change in tender point assessment. RESULTS: The mean age of study participants was 55 years, and 88% were female. Mean FIQ scores were significantly lower in the MoodGYM group compared to the control group (P<0.05 for group differences at 6 and 12 weeks). Mean tender point scores were also significantly lower in the MoodGYM group (P<0.001 at 6 and 12 weeks). We found no significant difference in the FIQ scores across the 3 timepoints in the MoodGYM group, but tender points showed a significant negative trend from baseline to 12-week follow-up. CONCLUSION:Patients in the internet-based MoodGYM CBT program had lower FIQ and tender point scores at 6- and 12-week follow-up. Internet-based CBT could be beneficial in the treatment of mild to moderate depression and anxiety in patients with fibromyalgia by allowing increased access to CBT.
Authors: Jesse H Wright; Laura W McCray; Tracy D Eells; Rangaraj Gopalraj; Laura B Bishop Journal: Curr Psychiatry Rep Date: 2018-09-07 Impact factor: 5.285
Authors: Nicola Luigi Bragazzi; Howard Amital; Mohammad Adawi; Francesco Brigo; Samaa Watad; Gali Aljadeff; Daniela Amital; Abdulla Watad Journal: Clin Rheumatol Date: 2017-05-01 Impact factor: 2.980
Authors: Miel A P Vugts; Margot C W Joosen; Jessica E van der Geer; Aglaia M E E Zedlitz; Hubertus J M Vrijhoef Journal: PLoS One Date: 2018-05-16 Impact factor: 3.240