Yongxue Zhang1, Qingsheng Lu2, Yifei Pei3, Mengtao Wu3, Suming Zhang3, Yi Hong3, Zaiping Jing4. 1. Division of Vascular Surgery, Changhai Hospital, Shanghai, China; Military Institute of Vascular Disease, the First Affiliated Hospital of the Second Military Medical University, Shanghai, China. 2. Division of Vascular Surgery, Changhai Hospital, Shanghai, China. Electronic address: luqs@xueguan.net. 3. Division of Vascular Surgery, Changhai Hospital, Shanghai, China. 4. Military Institute of Vascular Disease, the First Affiliated Hospital of the Second Military Medical University, Shanghai, China.
Abstract
BACKGROUND: Total endovascular repair of thoracoabdominal aortic aneurysms with customized branched or fenestrated endografts could be technically challenging outside large-volume centers. This study aims to describe a new endovascular strategy for use of both noncustomized stent grafts and flow-diverting stents in treating complicated thoracoabdominal aortic aneurysms. METHODS: Patients diagnosed with thoracoabdominal aortic aneurysms and deemed unfit for open surgical repair were recruited. The aim of the procedure was to cover the renovisceral segment of the aorta with flow-diverting uncovered stents, while covering the remaining aneurysm with stent grafts. Aneurysm morphologic evolution and the patency of the visceral branches were assessed at follow-up. RESULTS: Between February 2012 and August 2013, 6 selective patients (4 men, mean age 58 years) underwent the novel joint procedure. During mean follow-up of 14 months, aneurysm shrinkage (maximum diameter decrease ＞5 mm) was demonstrated in 4 patients and aneurysm stabilization (maximum diameter decrease ＜5 mm) was observed in 2 patients. No aneurysm expansion was observed in any participants. Mean aneurysm diameter decreased from 65.0±8.8 mm to 58.5±12.2 mm (p=0.054), with a significant increase in average sac thrombus deposition volume (sac thrombosis ratio increased from 23.3%±7.4% to 98.0%±3.3%, p＜0.001). The majority of side branches (23 of 24) were successfully preserved. CONCLUSIONS: Complete endovascular repair of thoracoabdominal aortic aneurysms with this novel joint procedure may be a feasible alternative in high surgical risk patients. Further validation of this technique is required to substantiate these results.
BACKGROUND: Total endovascular repair of thoracoabdominal aortic aneurysms with customized branched or fenestrated endografts could be technically challenging outside large-volume centers. This study aims to describe a new endovascular strategy for use of both noncustomized stent grafts and flow-diverting stents in treating complicated thoracoabdominal aortic aneurysms. METHODS:Patients diagnosed with thoracoabdominal aortic aneurysms and deemed unfit for open surgical repair were recruited. The aim of the procedure was to cover the renovisceral segment of the aorta with flow-diverting uncovered stents, while covering the remaining aneurysm with stent grafts. Aneurysm morphologic evolution and the patency of the visceral branches were assessed at follow-up. RESULTS: Between February 2012 and August 2013, 6 selective patients (4 men, mean age 58 years) underwent the novel joint procedure. During mean follow-up of 14 months, aneurysm shrinkage (maximum diameter decrease ＞5 mm) was demonstrated in 4 patients and aneurysm stabilization (maximum diameter decrease ＜5 mm) was observed in 2 patients. No aneurysm expansion was observed in any participants. Mean aneurysm diameter decreased from 65.0±8.8 mm to 58.5±12.2 mm (p=0.054), with a significant increase in average sac thrombus deposition volume (sac thrombosis ratio increased from 23.3%±7.4% to 98.0%±3.3%, p＜0.001). The majority of side branches (23 of 24) were successfully preserved. CONCLUSIONS: Complete endovascular repair of thoracoabdominal aortic aneurysms with this novel joint procedure may be a feasible alternative in high surgical risk patients. Further validation of this technique is required to substantiate these results.