Literature DB >> 25249016

Is hepatitis C virus eradication around the corner only 25 years after its discovery?

Giuseppe Ippolito1, Maria Rosaria Capobianchi1, Simone Lanini1, Guido Antonelli2.   

Abstract

Hepatitis C virus (HCV), identified approximately 25 years ago, is recognised as the cause of several clinical conditions besides chronic hepatitis. New compounds with direct antiviral activity have recently been introduced. These drugs promise to outdo old therapies based on interferon and ribavirin both in terms of improved safety and virological response. In fact, these drugs may pave the way to complete eradication of the disease. However, their actual price is exceedingly high and a strategy is necessary to guarantee wide and sustainable access to new therapies.
Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

Entities:  

Keywords:  Antiviral therapy; HCV; Hepatitis C virus

Mesh:

Substances:

Year:  2014        PMID: 25249016     DOI: 10.1016/j.ijantimicag.2014.09.001

Source DB:  PubMed          Journal:  Int J Antimicrob Agents        ISSN: 0924-8579            Impact factor:   5.283


  10 in total

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  10 in total

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