Literature DB >> 25248067

Intralesional cryosurgery to treat keloid scars: results from a retrospective study.

Marianne Chopinaud1, Anne-Dominique Pham, Daniel Labbé, Laurence Verneuil, Charlotte Gourio, Hervé Bénateau, Anne Dompmartin.   

Abstract

BACKGROUND: A variety of treatment modalities have been proposed to treat keloid scars, but outcomes are often disappointing. Intralesional cryosurgery may significantly reduce these scars.
OBJECTIVE: To evaluate the clinical safety and efficacy of intralesional cryosurgery to treat keloid scars. Feedback from patients on pain, pruritus and aesthetic discomfort was recorded before and after treatment.
METHODS: A total of 10 patients with 14 keloid scars resistant to conventional treatments were enrolled in a retrospective study between October 2007 and October 2013. The efficacy of this treatment was evaluated by measuring the reduction in scar surface.
RESULTS: Scar surface was reduced by an average of 58.5% after intralesional cryosurgery treatment for all scars (average pre-operative keloid scar surface: 874.6 ± 954.1 mm2; average post-operative keloid scar surface: 505.8 ± 1,024.7 mm2; p = 0.002). Pain and aesthetic discomfort were significantly decreased after treatment in all patients (p = 0.008 and p = 0.012, respectively).
CONCLUSION: Our data suggest that intralesional cryosurgery is an effective treatment for keloids.

Entities:  

Mesh:

Year:  2014        PMID: 25248067     DOI: 10.1159/000365392

Source DB:  PubMed          Journal:  Dermatology        ISSN: 1018-8665            Impact factor:   5.366


  3 in total

Review 1.  Israeli Innovations in the Field of Plastic Surgery.

Authors:  Lior Har-Shai; Sar-El Ofek; Stav Cohen; Keren H Cohen; Dafna Shilo Yaacobi; Asaf Olshinka; Rami P Dibbs; Dean D Ad-El
Journal:  Semin Plast Surg       Date:  2022-05-26       Impact factor: 2.195

Review 2.  Intralesional cryotherapy for hypertrophic scars and keloids: a review.

Authors:  Ciaran P O'Boyle; Holleh Shayan-Arani; Maha Wagdy Hamada
Journal:  Scars Burn Heal       Date:  2017-04-17

3.  Successful treatment of cutaneous squamous cell carcinoma with intralesional cryosurgery: Case report.

Authors:  Chaw-Ning Lee; Shin-Chen Pan; Julia Yu-Yun Lee; Tak-Wah Wong
Journal:  Medicine (Baltimore)       Date:  2016-09       Impact factor: 1.889

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.