Literature DB >> 25247829

Bi(OTf)3-catalyzed tandem Meyer-Schuster rearrangement and 1,4-addition to the resulting vinyl ketone.

Noriko Okamoto1, Takuya Sueda, Reiko Yanada.   

Abstract

Bi(OTf)3-catalyzed Meyer-Schuster rearrangement of electron-rich propargyl alcohols, followed by 1,4-addition of the resulting vinyl ketone, proceeded smoothly though Meyer-Schuster rearrangement of primary propargyl alcohols is rare. This tandem reaction can be extended to an intramolecular version, featuring a one-pot dihydroquinolone synthesis.

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Year:  2014        PMID: 25247829     DOI: 10.1021/jo5017663

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Design, synthesis and evaluation of novel 2,2-dimethyl-2,3-dihydroquinolin-4(1H)-one based chalcones as cytotoxic agents.

Authors:  Julie Jean; David S Farrell; Angela M Farrelly; Sinead Toomey; James W Barlow
Journal:  Heliyon       Date:  2018-09-04
  1 in total

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