Literature DB >> 25247747

24-h urinary free cortisol from mid-pregnancy to 3-months postpartum: gender and parity differences and effects.

Ana Conde1, Bárbara Figueiredo2.   

Abstract

BACKGROUND: Pregnancy and postpartum have been associated to several physiological changes; however, empirical evidence was almost exclusively obtained in primiparous women and few studies focus on hormonal changes in men and second-time parents. The main aim of this study is to examine 24-h urinary free cortisol from mid-pregnancy to 3-months postpartum, comparing women/men and first/second-time parents.
METHODS: Twenty-six women and 22 men (N=48) were recruited from an antenatal obstetric unit in Porto, Portugal. 24-h urinary free cortisol was measured at the 2nd and 3rd trimester and at 3-months postpartum. Repeated measures analyses of variance were conducted, in order to analyze 24-h urinary free cortisol patterns of change over this period. Gender and parity were included in the analyses as potential modifiers, in order to compare women and men, and first- and second-time parents.
RESULTS: An increase from the 2nd to the 3rd trimester (p=.006) and a decrease from the 3rd trimester to 3-months postpartum (p=.005) were reported in all parents' 24-h urinary free cortisol. The interaction effects for Time*Gender (p=.03) and Time*Parity (p=.02) were found. Women and first-time parents revealed higher levels, while men and second-time parents showed lower 24-h urinary free cortisol levels at the 2nd trimester than at 3-months postpartum.
CONCLUSIONS: Findings appear to clarify the direction, as well as, the timing, gender and parity extension of 24-h urinary free cortisol changes from mid-pregnancy to 3-months postpartum. The same pattern of change in all parents' 24-h urinary free cortisol from mid-pregnancy to 3-months postpartum is consistent with the proposed role of hormones in preparation to parenting. Gender and parity differences and effects on 24-h urinary free cortisol are also consistent with cortisol as a stress biomarker for higher challenges associated to pregnancy and childbirth in women and first-time parents versus higher demands related to after childbirth parenting in men and second-time parents.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  1st/2nd time parents; Cortisol; Postpartum; Pregnancy; Women/men

Mesh:

Substances:

Year:  2014        PMID: 25247747     DOI: 10.1016/j.psyneuen.2014.08.013

Source DB:  PubMed          Journal:  Psychoneuroendocrinology        ISSN: 0306-4530            Impact factor:   4.905


  8 in total

1.  Maternal parity and perinatal cortisol adaptation: The role of pregnancy-specific distress and implications for postpartum mood.

Authors:  Shannon L Gillespie; Amanda M Mitchell; Jennifer M Kowalsky; Lisa M Christian
Journal:  Psychoneuroendocrinology       Date:  2018-07-05       Impact factor: 4.905

2.  Seasonal variation in salivary cortisol but not symptoms of depression and trait anxiety in pregnant women undergoing an elective caesarean section.

Authors:  Samantha M Garay; Katrina A Savory; Lorna A Sumption; Richard J A Penketh; Ian R Jones; Anna B Janssen; Rosalind M John
Journal:  Psychoneuroendocrinology       Date:  2019-05-31       Impact factor: 4.905

3.  The validity of the residuals approach to measuring resilience to adverse childhood experiences.

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4.  Free Cortisol Mediates Associations of Maternal Urinary Heavy Metals with Neonatal Anthropometric Measures: A Cross-Sectional Study.

Authors:  Sohyeon Choi; Aram Lee; Gyuyeon Choi; Hyo-Bang Moon; Sungkyoon Kim; Kyungho Choi; Jeongim Park
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Review 5.  Urticaria in Pregnancy and Lactation.

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Journal:  Front Allergy       Date:  2022-07-07

Review 6.  The diagnosis and management of Cushing's syndrome in pregnancy.

Authors:  Ross Hamblin; Amy Coulden; Athanasios Fountas; Niki Karavitaki
Journal:  J Neuroendocrinol       Date:  2022-05-01       Impact factor: 3.870

7.  Comparison of women's stress in unexplained early pregnancy loss and normal vaginal delivery.

Authors:  Hajar Adib-Rad; Zahra Basirat; Mahbobeh Faramarzi; Amrollah Mostafazadeh; Ali Bijani; Marmar Firozpour Bandpy
Journal:  J Educ Health Promot       Date:  2020-01-30

8.  Parity-related variation in cortisol concentrations in hair during pregnancy.

Authors:  I Marteinsdottir; G Sydsjö; Å Faresjö; E Theodorsson; A Josefsson
Journal:  BJOG       Date:  2020-10-25       Impact factor: 6.531

  8 in total

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