Literature DB >> 2524749

[Efficacy and tolerance of tiaprofenic acid in pharyngitis in adults. Results of a randomized study vs placebo].

C Benarrosh1, A Ulmann.   

Abstract

Tiaprofenic acid (Surgam) is a non steroidal anti-inflammatory drug used in France for the treatment of acute inflammation, during episodes of upper respiratory tract infections of children and adults. The efficacy and tolerance of tiaprofenic acid for the treatment of inflammation during adult tonsillitis and pharyngitis were evaluated by a randomized double-blind study versus placebo. We used evaluation criterion taking into consideration dysphagia and inflammatory physical indications of tonsillitis and opinions of investigators and patients. Sixty patients have been included in this study. They received either tiaprofenic acid or placebo during five days together with penicillin V. After 48 hours and 5 days of treatment, the efficacy of tiaprofenic acid was significantly superior to placebo on all principal test studied. Tolerance was good in both groups.

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Year:  1989        PMID: 2524749

Source DB:  PubMed          Journal:  Presse Med        ISSN: 0755-4982            Impact factor:   1.228


  2 in total

Review 1.  How effective are treatments other than antibiotics for acute sore throat?

Authors:  M Thomas; C Del Mar; P Glasziou
Journal:  Br J Gen Pract       Date:  2000-10       Impact factor: 5.386

2.  Pharmacokinetics of tiaprofenic acid in children after a single oral dose.

Authors:  L Bertin; E Rey; G Pons; J L Mathiot; M O Richard; P Chrétien; C Saint-Maurice; C Moran; D Ginisty; G Olive
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

  2 in total

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