Literature DB >> 25247464

Short and efficient synthesis of fluorinated δ-lactams.

Thomas J Cogswell1, Craig S Donald, De-Liang Long, Rodolfo Marquez.   

Abstract

The diastereoselective synthesis of fluorinated δ-lactams has been achieved through an efficient five step process. The route can tolerate a range of functionalities, and provides a quick route for the generation of new fluorinated medicinal building blocks.

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Year:  2015        PMID: 25247464     DOI: 10.1039/c4ob01547a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Rapid, two-pot procedure for the synthesis of dihydropyridinones; total synthesis of aza-goniothalamin.

Authors:  Thomas J Cogswell; Craig S Donald; Rodolfo Marquez
Journal:  Beilstein J Org Chem       Date:  2020-01-28       Impact factor: 2.883

  1 in total

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