Literature DB >> 2524706

Acyclovir-resistant, foscarnet-sensitive oral herpes simplex type 2 lesion in a patient with AIDS.

L A MacPhail1, D Greenspan, M Schiødt, D P Drennan, J Mills.   

Abstract

We report the case of an immunocompromised patient with AIDS in whom developed a perioral and several intraoral HSV 2 lesions that persisted for more than 1 year. The virus was resistant to acyclovir but was sensitive to foscarnet. Viral isolates were thymidine kinase negative. The lesions resolved with intravenous foscarnet therapy given over a 15-week period, and when last seen, 8 months after foscarnet was discontinued, the patient had not had a recurrence.

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Year:  1989        PMID: 2524706     DOI: 10.1016/0030-4220(89)90386-1

Source DB:  PubMed          Journal:  Oral Surg Oral Med Oral Pathol        ISSN: 0030-4220


  2 in total

1.  Oral shedding of herpes simplex virus type 2.

Authors:  A Wald; M Ericsson; E Krantz; S Selke; L Corey
Journal:  Sex Transm Infect       Date:  2004-08       Impact factor: 3.519

2.  Herpes simplex virus type-2 ulcers resistant to acyclovir in an AIDS patient--successful treatment with foscarnet.

Authors:  H J Stellbrink; H Albrecht; T Löning; H Greten
Journal:  Klin Wochenschr       Date:  1991-04-04
  2 in total

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