Subinay Datta1, Mrinal Pal1, Anshuman DE2. 1. Department of Biochemistry, Burdwan Medical College, West Bengal University of Health Sciences, West Bengal, Pin-713101 India. 2. Department of Biochemistry, Malda Medical College, West Bengal University of Health Sciences, West Bengal, Pin-713101 India.
Abstract
BACKGROUND: Hypovitaminosis D appears to parallel several cardiovascular and pulmonary diseases. However, previous findings cannot be considered conclusive, since the association may have been confounded by different anthropometric variables that were not accounted for. The present cross-sectional study was conducted to investigate the association between important explanatory variables and circulation levels of vitamin D. METHODS: A total of 553 individuals attending the metabolic and medical lifestyle management clinic of the Burdwan district of India were selected from 1289 people by simple random sampling, and information regarding relevant variables and their blood was obtained. Serum 25-hydroxyvitamin (OH) D level and forced expiratory volume in 1 second were measured. Associations between different explanatory variables and circulatory 25(OH) D were analysed in linear regression models. RESULTS: Of the population studied, 53% had insufficient vitamin D levels, while approximately 9% were vitamin D deficient. Variables that significantly associated with lower 25(OH)D levels were obesity, current smoking, forced expiratory volume 1 and depression. CONCLUSION: Lower serum levels of vitamin D were associated with different variables that should be explored in several diseases before a conclusion of hypovitaminosis D is drawn.
BACKGROUND: Hypovitaminosis D appears to parallel several cardiovascular and pulmonary diseases. However, previous findings cannot be considered conclusive, since the association may have been confounded by different anthropometric variables that were not accounted for. The present cross-sectional study was conducted to investigate the association between important explanatory variables and circulation levels of vitamin D. METHODS: A total of 553 individuals attending the metabolic and medical lifestyle management clinic of the Burdwan district of India were selected from 1289 people by simple random sampling, and information regarding relevant variables and their blood was obtained. Serum 25-hydroxyvitamin (OH) D level and forced expiratory volume in 1 second were measured. Associations between different explanatory variables and circulatory 25(OH) D were analysed in linear regression models. RESULTS: Of the population studied, 53% had insufficient vitamin D levels, while approximately 9% were vitamin D deficient. Variables that significantly associated with lower 25(OH)D levels were obesity, current smoking, forced expiratory volume 1 and depression. CONCLUSION: Lower serum levels of vitamin D were associated with different variables that should be explored in several diseases before a conclusion of hypovitaminosis D is drawn.
Entities:
Keywords:
25(OH)D; confounding variables; obesity; vitamin D; vitamin D deficiency