Eun Soo Kim1, Kyung Sik Park1, Kwang Bum Cho1, Kyeong Ok Kim2, Byung Ik Jang2, Eun Young Kim3, Jin Tae Jung3, Seong Woo Jeon4, Min Kyu Jung4, Hyun Seok Lee4, Chang Heon Yang5, Yong Kook Lee5. 1. Division of Gastroenterology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea. 2. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Republic of Korea. 3. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Republic of Korea. 4. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea. 5. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Dongguk University School of Medicine, Gyeongju, Gyeongsang-buk-do, Republic of Korea.
Abstract
BACKGROUND AND AIMS: Crohn's Disease Activity Index (CDAI) is complex, time-consuming, and impractical. The aim of this study was to investigate whether a newly developed, simple, web-based self-reporting Crohn's Disease symptom diary (CDSD) was as effective as CDAI in assessing disease severity. METHODS: CDSD consisted of 5 clinical parameters based on the Harvey-Bradshaw Index (HBI), which could easily be recorded online, by using CDSD website (www.cdsd.or.kr). Images were added to help patients better understand complications. All patients were asked to visit the website and record their symptoms 7 days before their next hospital appointment. CDAI scores were calculated at the subsequent hospital visit. The collected data were analyzed to determine if the CDAI scores correlated with those obtained from CDSD, and to define a cut-off value of CDSD that would be representative of disease remission. RESULTS: Analysis of 171 visits showed a positive correlation between scores from CDSD and CDAI (Spearman correlation coefficient r = 0.720, p < 0.001). Receiver Operating Characteristic curves showed CDSD score ≤5 points as corresponding with CDAI score ≤150 points (clinical remission). Using a cut-off value of 5 points by CDSD, the positive and negative predictive values for clinical remission were 91.7% and 88.5%, respectively. CONCLUSION: This study demonstrates that CDSD correlated well with CDAI. CDSD score of 5 is the cut-off value for clinical remission (CDAI score ≤150). Use of CDSD might permit a simple, patient-friendly assessment of CD activity, which can provide useful early-phase information on patients with CD as part of their long-term clinical assessment.
BACKGROUND AND AIMS: Crohn's Disease Activity Index (CDAI) is complex, time-consuming, and impractical. The aim of this study was to investigate whether a newly developed, simple, web-based self-reporting Crohn's Disease symptom diary (CDSD) was as effective as CDAI in assessing disease severity. METHODS: CDSD consisted of 5 clinical parameters based on the Harvey-Bradshaw Index (HBI), which could easily be recorded online, by using CDSD website (www.cdsd.or.kr). Images were added to help patients better understand complications. All patients were asked to visit the website and record their symptoms 7 days before their next hospital appointment. CDAI scores were calculated at the subsequent hospital visit. The collected data were analyzed to determine if the CDAI scores correlated with those obtained from CDSD, and to define a cut-off value of CDSD that would be representative of disease remission. RESULTS: Analysis of 171 visits showed a positive correlation between scores from CDSD and CDAI (Spearman correlation coefficient r = 0.720, p < 0.001). Receiver Operating Characteristic curves showed CDSD score ≤5 points as corresponding with CDAI score ≤150 points (clinical remission). Using a cut-off value of 5 points by CDSD, the positive and negative predictive values for clinical remission were 91.7% and 88.5%, respectively. CONCLUSION: This study demonstrates that CDSD correlated well with CDAI. CDSD score of 5 is the cut-off value for clinical remission (CDAI score ≤150). Use of CDSD might permit a simple, patient-friendly assessment of CD activity, which can provide useful early-phase information on patients with CD as part of their long-term clinical assessment.
Authors: Eva-Maria Messner; Niklas Sturm; Yannik Terhorst; Lasse B Sander; Dana Schultchen; Alexandra Portenhauser; Simone Schmidbaur; Michael Stach; Jochen Klaus; Harald Baumeister; Benjamin M Walter Journal: J Med Internet Res Date: 2022-10-05 Impact factor: 7.076
Authors: Da Eun Jeong; Kyeong Ok Kim; Byung Ik Jang; Eun Young Kim; Jin Tae Jung; Seong Woo Jeon; Hyun Seok Lee; Eun Soo Kim; Kyung Sik Park; Kwang Bum Cho Journal: Medicine (Baltimore) Date: 2016-06 Impact factor: 1.889
Authors: Eun Soo Kim; Yoo Jin Lee; Byung Ik Jang; Kyeong Ok Kim; Eun Young Kim; Hyun Seok Lee; Seong Woo Jeon; Sang Gyu Kwak Journal: Korean J Intern Med Date: 2018-01-17 Impact factor: 2.884