Literature DB >> 25243250

Efficient approach to prepare multiple chemotherapeutic agent conjugated nanocarrier.

Vijayakameswara Rao N1, Himadri Dinda, Mutyala Naidu Ganivada, Jayasri Das Sarma, Raja Shunmugam.   

Abstract

A pH-responsive, multiple chemotherapeutic agent derived nanocarrier has been synthesized by conjugating doxorubicin, indomethacin, and folate to the backbone of norbornene polymer. Drug molecules are connected to the norbornene backbone by an ester linker to demonstrate the pH-responsive capabilities. The complete chemical and biological properties of the new norbornene-based polymeric nanocarrier, intended for combination cancer chemotherapy, are discussed.

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Year:  2014        PMID： 25243250     DOI： 10.1039/c4cc04445b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  Recent Progress and Advances in Stimuli-Responsive Polymers for Cancer Therapy.

Authors:  N Vijayakameswara Rao; Hyewon Ko; Jeongjin Lee; Jae Hyung Park
Journal:  Front Bioeng Biotechnol       Date:  2018-08-13

2.  A carboxymethyl dextran-based polymeric conjugate as the antigen carrier for cancer immunotherapy.

Authors:  Jung Min Shin; Seok Ho Song; N Vijayakameswara Rao; Eun Sook Lee; Hyewon Ko; Jae Hyung Park
Journal:  Biomater Res       Date:  2018-08-14

3.  pH-Sensitive Nanoaggregates for Site-Specific Drug-Delivery as Well as Cancer Cell Imaging.

Authors:  Saikat Mukherjee; Jayasri Das Sarma; Raja Shunmugam
Journal:  ACS Omega       Date:  2016-11-01

4.  Nanotechnology-based combination therapy for overcoming multidrug-resistant cancer.

Authors:  Meng Zhang; Ergang Liu; Yanna Cui; Yongzhuo Huang
Journal:  Cancer Biol Med       Date:  2017-08       Impact factor: 4.248
  4 in total

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