S Reid Lester1, Kitrina G Cordell2, Molly S Rosebush3, A Archontia Palaiologou4, Pooja Maney5. 1. Postgraduate Resident, Department of Periodontics, Louisiana State University Health Science Center School of Dentistry, New Orleans, LA, USA. 2. Associate Professor, Division of Oral and Maxillofacial Pathology, Louisiana State University Health Science Center School of Dentistry, New Orleans, LA, USA. 3. Assistant Professor, Division of Oral and Maxillofacial Pathology, Louisiana State University Health Science Center School of Dentistry, New Orleans, LA, USA. 4. Associate Professor, Department of Periodontics, Louisiana State University Health Science Center School of Dentistry, New Orleans, LA, USA. Electronic address: Apalai@lsuhsc.edu. 5. Assistant Professor, Department of Periodontics, Louisiana State University Health Science Center School of Dentistry, New Orleans, LA, USA.
Abstract
OBJECTIVE: This study investigated the demographic, clinicopathologic, and histopathologic findings of lesions diagnosed as peripheral giant cell granuloma (PGCG) by the Louisiana State University Oral Pathology Biopsy Service from 1974 to 2011. STUDY DESIGN: Clinical, demographic, and histopathologic evaluation was completed for 279 cases. A follow-up questionnaire was mailed to all surgeons who performed these biopsies from 1990 to 2011. RESULTS: Of the 279 lesions, 58% occurred in the mandible, 44% occurred in the anterior portion of the arches, 83% were adjacent to teeth, 14% occurred in edentulous areas, and 2% were adjacent to implants. Average duration was 10.5 months, and the average size was 12.7 mm. The recurrence rate was 17.5%. Histopathologically, 78% of lesions extended to the base of the specimen, 50% exhibited ulceration, 41% contained calcifications, and 6% exhibited features overlapping with another pathologic entity. CONCLUSIONS: PGCG is a well-defined pathologic entity among reactive gingival lesions. Recurrent lesions were more likely to contain calcifications.
OBJECTIVE: This study investigated the demographic, clinicopathologic, and histopathologic findings of lesions diagnosed as peripheral giant cell granuloma (PGCG) by the Louisiana State University Oral Pathology Biopsy Service from 1974 to 2011. STUDY DESIGN: Clinical, demographic, and histopathologic evaluation was completed for 279 cases. A follow-up questionnaire was mailed to all surgeons who performed these biopsies from 1990 to 2011. RESULTS: Of the 279 lesions, 58% occurred in the mandible, 44% occurred in the anterior portion of the arches, 83% were adjacent to teeth, 14% occurred in edentulous areas, and 2% were adjacent to implants. Average duration was 10.5 months, and the average size was 12.7 mm. The recurrence rate was 17.5%. Histopathologically, 78% of lesions extended to the base of the specimen, 50% exhibited ulceration, 41% contained calcifications, and 6% exhibited features overlapping with another pathologic entity. CONCLUSIONS: PGCG is a well-defined pathologic entity among reactive gingival lesions. Recurrent lesions were more likely to contain calcifications.
Authors: Martina C Schwerzmann; Matthias S Dettmer; Daniel Baumhoer; Tateyuki Iizuka; Valerie G A Suter Journal: BMC Oral Health Date: 2022-09-05 Impact factor: 3.747
Authors: Carolina Cavalieri Gomes; Tenzin Gayden; Andrea Bajic; Osama F Harraz; Jonathan Pratt; Hamid Nikbakht; Eric Bareke; Marina Gonçalves Diniz; Wagner Henriques Castro; Pascal St-Onge; Daniel Sinnett; HyeRim Han; Barbara Rivera; Leonie G Mikael; Nicolas De Jay; Claudia L Kleinman; Elvis Terci Valera; Angelia V Bassenden; Albert M Berghuis; Jacek Majewski; Mark T Nelson; Ricardo Santiago Gomez; Nada Jabado Journal: Nat Commun Date: 2018-11-01 Impact factor: 14.919