Literature DB >> 2523806

In vitro activity of trospectomycin (U-63366F), a novel spectinomycin analog, against gram-positive isolates from cancer patients.

K Rolston1, D H Ho, G P Bodey.   

Abstract

The in vitro activity of trospectomycin was compared to that of amikacin, cephalothin and vancomycin against gram-positive organisms, mostly isolated from cancer patients. Trospectomycin was considerably more active than amikacin against most isolates tested, particularly species of Staphylococcus and Streptococcus. Overall, vancomycin was the most active agent tested.

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Year:  1989        PMID： 2523806     DOI： 10.1007/bf01965272

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN： 0934-9723            Impact factor:   3.267


  5 in total

1.  Activity of trospectomycin against Bacteroides fragilis and other Bacteroides species.

Authors:  N V Jacobus; F P Tally
Journal:  Antimicrob Agents Chemother       Date:  1988-04       Impact factor: 5.191

2.  In vitro antibacterial activity of trospectomycin (U-63366F), a novel spectinomycin analog.

Authors:  G E Zurenko; B H Yagi; J J Vavra; B B Wentworth
Journal:  Antimicrob Agents Chemother       Date:  1988-02       Impact factor: 5.191

3.  The tolerance of high dose intravenous spectinomycin therapy in man.

Authors:  E Novak; C A Schlagel; L A LeZotte; R T Pfeifer
Journal:  J Clin Pharmacol       Date:  1974 Aug-Sep       Impact factor: 3.126

4.  Neutropenia, fever, and infection.

Authors:  A E Brown
Journal:  Am J Med       Date:  1984-03       Impact factor: 4.965

Review 5.  Antibiotic therapy of nonenterococcal streptococcal and staphylococcal endocarditis: current regimens and some future considerations.

Authors:  A W Karchmer
Journal:  J Antimicrob Chemother       Date:  1988-04       Impact factor: 5.790
  5 in total

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