Literature DB >> 25236340

HDGF: a novel jack-of-all-trades in cancer.

Cihang Bao1, Jianbo Wang, Wei Ma, Xintong Wang, Yufeng Cheng.   

Abstract

HDGF is an important regulator of a broad range of cancer cell activities and plays important roles in cancer cell transformation, apoptosis, angiogenesis and metastasis. Such a divergent influence of HDGF on cancer cell activities derives from its multiple inter- and sub-cellular localizations where it interacts with a range of different binding partners. Interestingly, high levels of HDGF could be detected in patients' serum of some cancers. This review is focused on the role of HDGF in tumorigenesis and metastasis, and provides insight for application in clinical cancer therapy as well as its clinical implications as a prognostic marker in cancer progression.

Entities:  

Keywords:  PWWP/HATH domain; angiogenesis; apoptosis; epithelial-to-mesencyhmal transition; hepatoma-derived growth factor; metastasis; molecular mechanisms; prognosis; serum levels; tumorigenesis

Mesh：

Substances：

Year:  2014        PMID： 25236340     DOI： 10.2217/fon.14.194

Source DB:  PubMed          Journal:  Future Oncol        ISSN： 1479-6694            Impact factor:   3.404


  36 in total

1.  Reactive Oxygen Species (ROS)-Activated ATM-Dependent Phosphorylation of Cytoplasmic Substrates Identified by Large-Scale Phosphoproteomics Screen.

Authors:  Sergei V Kozlov; Ashley J Waardenberg; Kasper Engholm-Keller; Jonathan W Arthur; Mark E Graham; Martin Lavin
Journal:  Mol Cell Proteomics       Date:  2015-12-23       Impact factor: 5.911

Review 2.  Bioactive supplements influencing bovine in vitro embryo development.

Authors:  Lydia K Wooldridge; Jessica A Keane; Michelle L Rhoads; Alan D Ealy
Journal:  J Anim Sci       Date:  2022-07-01       Impact factor: 3.338

Review 3.  Long Noncoding RNAs and Circular RNAs in the Metabolic Reprogramming of Lung Cancer: Functions, Mechanisms, and Clinical Potential.

Authors:  Yuhao Zhou; Yuan Zhan; Weiling Jiang; Huiguo Liu; Shuang Wei
Journal:  Oxid Med Cell Longev       Date:  2022-06-15       Impact factor: 7.310

4.  Progranulin and granulin-like protein as novel VEGF-independent angiogenic factors derived from human mesothelioma cells.

Authors:  R Eguchi; T Nakano; I Wakabayashi
Journal:  Oncogene       Date:  2016-06-27       Impact factor: 9.867

5.  Hepatocellular Carcinoma-associated microRNAs Induced by Hepatoma-derived Growth Factor Stimulation.

Authors:  Hirayuki Enomoto; Hideji Nakamura; Hiroki Nishikawa; Takashi Nishimura; Yoshinori Iwata; Shuhei Nishiguchi; Hiroko Iijima
Journal:  In Vivo       Date:  2020 Sep-Oct       Impact factor: 2.155

6.  Recurrent co-alteration of HDGF and SETDB1 on chromosome 1q drives cutaneous melanoma progression and poor prognosis.

Authors:  Maurizio Fazio; Ellen van Rooijen; Jeffrey K Mito; Rodsy Modhurima; Erika Weiskopf; Song Yang; Leonard I Zon
Journal:  Pigment Cell Melanoma Res       Date:  2020-11-17       Impact factor: 4.693

7.  The expression and clinical significance of HDGF in osteosarcoma.

Authors:  Zhiguo Chen; Shenghai Qiu; Xiaofei Lu
Journal:  Onco Targets Ther       Date:  2015-09-09       Impact factor: 4.147

8.  Hepatoma-derived growth factor predicts unfavorable prognosis of epithelial ovarian cancer.

Authors:  Xue-Jun Liu; Wen-Lian Liu; Fang-Mei Yang; Xiao-Qing Yang; Xiao-Fei Lu
Journal:  Onco Targets Ther       Date:  2015-08-13       Impact factor: 4.147

9.  Establishment of a Prognostic Model for Hepatocellular Carcinoma Based on Endoplasmic Reticulum Stress-Related Gene Analysis.

Authors:  Peng Liu; Jinhong Wei; Feiyu Mao; Zechang Xin; Heng Duan; Yan Du; Xiaodong Wang; Zhennan Li; Jianjun Qian; Jie Yao
Journal:  Front Oncol       Date:  2021-05-21       Impact factor: 6.244

10.  Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice.

Authors:  Hao Wang; Ming-Chieh Shun; Amy K Dickson; Alan N Engelman
Journal:  PLoS One       Date:  2015-09-14       Impact factor: 3.240
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