Literature DB >> 25234722

Haemoglobin wrapped covalently by human serum albumin mutants containing Mn(III) protoporphyrin IX: an O2 complex stable in H2O2 solution.

Y Daijima1, T Komatsu.   

Abstract

We describe the synthesis of a haemoglobin (Hb) wrapped covalently by recombinant human serum albumin mutants [HSA(Y161H)] containing Mn(III) protoporphyrin IX (MnPP), the Hb-[HSA(Y161H)-MnPP]3 cluster, highlighting the formation of its O2-complex stable even in H2O2 solution.

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Year:  2014        PMID： 25234722     DOI： 10.1039/c4cc06076h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Influence of Molecular Structure on O2-Binding Properties and Blood Circulation of Hemoglobin‒Albumin Clusters.

Authors:  Kana Yamada; Kyoko Yokomaku; Risa Haruki; Kazuaki Taguchi; Saori Nagao; Toru Maruyama; Masaki Otagiri; Teruyuki Komatsu
Journal:  PLoS One       Date:  2016-02-19       Impact factor: 3.240

Review 2.  The Red Color of Life Transformed - Synthetic Advances and Emerging Applications of Protoporphyrin IX in Chemical Biology.

Authors:  Elisabeth Sitte; Mathias O Senge
Journal:  European J Org Chem       Date:  2020-03-30

3.  Low-intensity pulsed ultrasound-generated singlet oxygen induces telomere damage leading to glioma stem cell awakening from quiescence.

Authors:  Sirong Song; Dongbin Ma; Lixia Xu; Qiong Wang; Lanxiang Liu; Xiaoguang Tong; Hua Yan
Journal:  iScience       Date:  2021-12-02

4.  Safety Evaluation of Hemoglobin-Albumin Cluster "HemoAct" as a Red Blood Cell Substitute.

Authors:  Risa Haruki; Takuya Kimura; Hitomi Iwasaki; Kana Yamada; Ikuo Kamiyama; Mitsutomo Kohno; Kazuaki Taguchi; Saori Nagao; Toru Maruyama; Masaki Otagiri; Teruyuki Komatsu
Journal:  Sci Rep       Date:  2015-07-29       Impact factor: 4.379
  4 in total

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