Literature DB >> 25232185

A case for crowd sourcing in stem cell research.

Olaf M Dekkers1, Christine L Mummery2, Ton J Rabelink3.   

Abstract

Thousands of patients and placebo-treated controls have been included in many clinical trials of stem cell therapy over the last decade or so, but often the study groups have been small. Their scientific value may therefore be limited and their ethical justification questionable. Would "crowd sourcing" for data sharing be a means of increasing the collective value of clinical trials? Here, we make a case for open access of all data emerging from stem cell studies (trials but also observational studies) independent of whether they are investigator-initiated or commercially driven. ©AlphaMed Press.

Entities:  

Mesh:

Year:  2014        PMID: 25232185      PMCID: PMC4214850          DOI: 10.5966/sctm.2014-0125

Source DB:  PubMed          Journal:  Stem Cells Transl Med        ISSN: 2157-6564            Impact factor:   6.940


  12 in total

1.  External validity of randomised controlled trials: "to whom do the results of this trial apply?".

Authors:  Peter M Rothwell
Journal:  Lancet       Date:  2005 Jan 1-7       Impact factor: 79.321

2.  The global landscape of stem cell clinical trials.

Authors:  Matthew D Li; Harold Atkins; Tania Bubela
Journal:  Regen Med       Date:  2013-11-18       Impact factor: 3.806

3.  Stamina therapies: Time to call a halt.

Authors:  Silvio Garattini; Giuseppe Remuzzi; Gianluca Vago; Alberto Zangrillo
Journal:  Nature       Date:  2014-02-27       Impact factor: 49.962

4.  Stem-cell method faces fresh questions.

Authors:  David Cyranoski
Journal:  Nature       Date:  2014-03-20       Impact factor: 49.962

5.  White paper on how to go forward with cell-based advanced therapies in Europe.

Authors:  Reinhold G Erben; Beatriz Silva-Lima; Ilona Reischl; Gustav Steinhoff; Gudrun Tiedemann; Wilfried Dalemans; Alexander Vos; Rob T A Janssen; Katarina Le Blanc; Gerjo J V M van Osch; Frank P Luyten
Journal:  Tissue Eng Part A       Date:  2014-06-03       Impact factor: 3.845

Review 6.  Meta-analyses of adverse effects data derived from randomised controlled trials as compared to observational studies: methodological overview.

Authors:  Su Golder; Yoon K Loke; Martin Bland
Journal:  PLoS Med       Date:  2011-05-03       Impact factor: 11.069

7.  Crowd sourcing a new paradigm for interactome driven drug target identification in Mycobacterium tuberculosis.

Authors:  Rohit Vashisht; Anupam Kumar Mondal; Akanksha Jain; Anup Shah; Priti Vishnoi; Priyanka Priyadarshini; Kausik Bhattacharyya; Harsha Rohira; Ashwini G Bhat; Anurag Passi; Keya Mukherjee; Kumari Sonal Choudhary; Vikas Kumar; Anshula Arora; Prabhakaran Munusamy; Ahalyaa Subramanian; Aparna Venkatachalam; S Gayathri; Sweety Raj; Vijaya Chitra; Kaveri Verma; Salman Zaheer; J Balaganesh; Malarvizhi Gurusamy; Mohammed Razeeth; Ilamathi Raja; Madhumohan Thandapani; Vishal Mevada; Raviraj Soni; Shruti Rana; Girish Muthagadhalli Ramanna; Swetha Raghavan; Sunil N Subramanya; Trupti Kholia; Rajesh Patel; Varsha Bhavnani; Lakavath Chiranjeevi; Soumi Sengupta; Pankaj Kumar Singh; Naresh Atray; Swati Gandhi; Tiruvayipati Suma Avasthi; Shefin Nisthar; Meenakshi Anurag; Pratibha Sharma; Yasha Hasija; Debasis Dash; Arun Sharma; Vinod Scaria; Zakir Thomas; Nagasuma Chandra; Samir K Brahmachari; Anshu Bhardwaj
Journal:  PLoS One       Date:  2012-07-11       Impact factor: 3.240

Review 8.  Discrepancies in autologous bone marrow stem cell trials and enhancement of ejection fraction (DAMASCENE): weighted regression and meta-analysis.

Authors:  Alexandra N Nowbar; Michael Mielewczik; Maria Karavassilis; Hakim-Moulay Dehbi; Matthew J Shun-Shin; Siana Jones; James P Howard; Graham D Cole; Darrel P Francis
Journal:  BMJ       Date:  2014-04-28

Review 9.  Non-publication of large randomized clinical trials: cross sectional analysis.

Authors:  Christopher W Jones; Lara Handler; Karen E Crowell; Lukas G Keil; Mark A Weaver; Timothy F Platts-Mills
Journal:  BMJ       Date:  2013-10-29

10.  Standardization of whole blood immune phenotype monitoring for clinical trials: panels and methods from the ONE study.

Authors:  Mathias Streitz; Tewfik Miloud; Michael Kapinsky; Michael R Reed; Robert Magari; Edward K Geissler; James A Hutchinson; Katrin Vogt; Stephan Schlickeiser; Anders Handrup Kverneland; Christian Meisel; Hans-Dieter Volk; Birgit Sawitzki
Journal:  Transplant Res       Date:  2013-10-25
View more
  1 in total

Review 1.  Ethical considerations in tissue engineering research: Case studies in translation.

Authors:  Hannah B Baker; John P McQuilling; Nancy M P King
Journal:  Methods       Date:  2015-08-14       Impact factor: 3.608

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.