Literature DB >> 25232129

Extracellular matrix for reconstruction of cardiac structures after tumour resections.

Simon H Sündermann1, Oliver Müggler2, Etem Caliskan2, Diana Reser2, Robert Manka3, Tomas Holubec2, Martin Czerny2, Volkmar Falk2.   

Abstract

OBJECTIVES: To describe the use of a new extracellular matrix patch as a means for atrial reconstruction in patients with cardiac tumours.
METHODS: A new extracellular matrix patch was used to reconstruct atrial and neighbouring structures after tumour resections. In 1 case, it was used to reconstruct the atrial septum and the left atrial roof after excision of a huge myxoma. In a second case, it was used to reconstruct the right atrium, including the superior vena cava after excision of a primary cardiac sarcoma. In a third case, it was used to reconstruct both atria, the right-sided pulmonary venous confluence and the roof of the coronary sinus after excision of a metastasis of malignant melanoma.
RESULTS: In all cases, reconstruction was successful and facilitated because of the flexible and thin character of the extracellular matrix, which also seemed to be advantageous with regards to haemostasis.
CONCLUSIONS: Extracellular matrix patches are a potential alternative for pericardial patches for complex reconstructions of atrial structures because of their pliable characteristics and consecutively reduced need for haemostatic stitches.
© The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

Entities:  

Keywords:  Cardiac reconstruction; Cardiac sarcoma; Extracellular matrix

Mesh:

Year:  2014        PMID: 25232129     DOI: 10.1093/icvts/ivu310

Source DB:  PubMed          Journal:  Interact Cardiovasc Thorac Surg        ISSN: 1569-9285


  1 in total

1.  Acellularization-Induced Changes in Tensile Properties Are Organ Specific - An In-Vitro Mechanical and Structural Analysis of Porcine Soft Tissues.

Authors:  Stefan Schleifenbaum; Torsten Prietzel; Gabriela Aust; Andreas Boldt; Sebastian Fritsch; Isabel Keil; Holger Koch; Robert Möbius; Holger A Scheidt; Martin F X Wagner; Niels Hammer
Journal:  PLoS One       Date:  2016-03-09       Impact factor: 3.240

  1 in total

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