Literature DB >> 25229858

Loss of ATP-dependent lysine uptake in the vacuolar membrane vesicles of Saccharomyces cerevisiae ypq1∆ mutant.

Takayuki Sekito1, Kyosuke Nakamura, Kunio Manabe, Junichi Tone, Yumika Sato, Nami Murao, Miyuki Kawano-Kawada, Yoshimi Kakinuma.   

Abstract

Saccharomyces cerevisiae Ypq1p is a vacuolar membrane protein of the PQ-loop protein family. We found that ATP-dependent uptake activities of amino acids by vacuolar membrane vesicles were impaired by ypq1∆ mutation. Loss of lysine uptake was most remarkable, and the uptake was recovered by overproduction of Ypq1p. Ypq1p is thus involved in transport of amino acids into vacuoles.

Entities:  

Keywords:  PQ-loop; lysine; transport; vacuole

Mesh：

Substances：

Year:  2014        PMID： 25229858     DOI： 10.1080/09168451.2014.918489

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  9 in total

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  9 in total

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