Amyloid ophthalmoplegia. Ophthalmoparesis secondary to primary systemic amyloidosis.

We report a patient with primary systemic amyloidosis and orbital involvement associated with ophthalmoparesis. We support this with the first demonstration of eye movement recordings and magnetic resonance imaging (MRI) of such a patient. The patient presented with a restrictive ophthalmoparesis. Eye movement recordings documented slowed horizontal saccades. MRI of orbital structures suggests that all extraocular muscles were enlarged, with possible involvement of their tendinous insertions.