C K Indumathi1, Priyadarashini M Kowtal, R N Poornima, Sanjiv Lewin. 1. Department of Pediatrics, St. John's Medical College Hospital, Bangalore, India. Correspondence to: Dr CK Indumathi, Associate Professor, Department of Pediatrics, St John's Medical College Hospital, Sarjapur Road, Bangalore 560 034, Karnataka, India. ckindumathi@gmail.com.
Abstract
OBJECTIVE: To describe the clinical profile, immunological status and outcome of BCG disease in infants. METHODS: All infants with a diagnosis of BCG disease in a period of 17 months were followed up. RESULTS: Among 25 infants with BCG disease; 19 had local/regional involvement and 6 had suspected or confirmed distant/disseminated disease, Mean (range) age of presentation was 3.6 (1.5-9) months. Two of 6 infants with disseminated disease required second-line anti-tubercular treatment. One infant with confirmed disseminated disease had INFg R1 receptor deficiency. There was no mortality. CONCLUSION: Most infants with BCG- related disease have local or regional disease.
OBJECTIVE: To describe the clinical profile, immunological status and outcome of BCG disease in infants. METHODS: All infants with a diagnosis of BCG disease in a period of 17 months were followed up. RESULTS: Among 25 infants with BCG disease; 19 had local/regional involvement and 6 had suspected or confirmed distant/disseminated disease, Mean (range) age of presentation was 3.6 (1.5-9) months. Two of 6 infants with disseminated disease required second-line anti-tubercular treatment. One infant with confirmed disseminated disease had INFg R1 receptor deficiency. There was no mortality. CONCLUSION: Most infants with BCG- related disease have local or regional disease.