Literature DB >> 25228227

Clostridium difficile ribotype 027 is most prevalent among inpatients admitted from long-term care facilities.

L R Archbald-Pannone1, J H Boone2, R J Carman2, D M Lyerly2, R L Guerrant3.   

Abstract

Intestinal inflammation was evaluated using faecal lactoferrin and ribotype in 196 hospitalized adults with Clostridium difficile infection to determine the impact of ribotype 027 in long-term care facilities (LTCFs). LTCF residents (n=28) had greater antibiotic use (P=0.049) and more ribotype 027 infection [odds ratio (OR): 4.87; 95% confidence interval (CI): 2.02-11.74; P<0.01], compared to those admitted from home. Patients infected with ribotype 027 strains had worse six-month mortality (OR: 1.90; 95% CI: 1.08-3.34; P=0.03) and more inflammation (95.26 vs 36.08 μg/mL; P=0.006), compared to those infected with non-027 strains. This study was not designed to determine acquisition site, but, in this population, suggests that the location from which the patient has been admitted is strongly associated with ribotype 027 and more severe C. difficile disease.
Copyright © 2014 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Clostridium difficile infection; Long-term care residents; Nosocomial diarrhoea; Strain BI/NAP1/027

Mesh：

Substances：

Year:  2014        PMID： 25228227      PMCID： PMC4250408          DOI： 10.1016/j.jhin.2014.06.016

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN： 0195-6701            Impact factor:   3.926


  9 in total

1.  Diarrhea, clostridium difficile, and intestinal inflammation in residents of a long-term care facility.

Authors:  Laurie Archbald-Pannone; Jesus Emmanuel Sevilleja; Richard Guerrant
Journal:  J Am Med Dir Assoc       Date:  2010-03-15       Impact factor: 4.669

2.  Clostridium difficile infection in a long-term care facility: hospital-associated illness compared with long-term care-associated illness.

Authors:  Jong Hun Kim; Diana Toy; Robert R Muder
Journal:  Infect Control Hosp Epidemiol       Date:  2011-07       Impact factor: 3.254

3.  Clostridium difficile ribotype does not predict severe infection.

Authors:  Seth T Walk; Dejan Micic; Ruchika Jain; Eugene S Lo; Itishree Trivedi; Eugene W Liu; Luay M Almassalha; Sarah A Ewing; Cathrin Ring; Andrzej T Galecki; Mary A M Rogers; Laraine Washer; Duane W Newton; Preeti N Malani; Vincent B Young; David M Aronoff
Journal:  Clin Infect Dis       Date:  2012-09-12       Impact factor: 9.079

Review 4.  Clostridium difficile in long-term-care facilities for the elderly.

Authors:  Andrew E Simor; Suzanne F Bradley; Larry J Strausbaugh; Kent Crossley; Lindsay E Nicolle
Journal:  Infect Control Hosp Epidemiol       Date:  2002-11       Impact factor: 3.254

5.  Elevated levels of intestinal inflammation in Clostridium difficile infection associated with fluoroquinolone-resistant C. difficile.

Authors:  S W Pawlowski; L Archbald-Pannone; R J Carman; C Alcantara-Warren; D Lyerly; C W Genheimer; D N Gerding; R L Guerrant
Journal:  J Hosp Infect       Date:  2009-08-26       Impact factor: 3.926

6.  Effect of ribotype on all-cause mortality following Clostridium difficile infection.

Authors:  T Inns; R Gorton; A Berrington; A Sails; T Lamagni; J Collins; J Perry; K Hill; J Magee; K Gould
Journal:  J Hosp Infect       Date:  2013-06-10       Impact factor: 3.926

Review 7.  Clostridium difficile infection: new developments in epidemiology and pathogenesis.

Authors:  Maja Rupnik; Mark H Wilcox; Dale N Gerding
Journal:  Nat Rev Microbiol       Date:  2009-07       Impact factor: 60.633

8.  Ribotype 027 Clostridium difficile infections with measurable stool toxin have increased lactoferrin and are associated with a higher mortality.

Authors:  J H Boone; L R Archbald-Pannone; K N Wickham; R J Carman; R L Guerrant; C T Franck; D M Lyerly
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-01-22       Impact factor: 3.267

9.  Increase in Clostridium difficile-related mortality rates, United States, 1999-2004.

Authors:  Matthew D Redelings; Frank Sorvillo; Laurene Mascola
Journal:  Emerg Infect Dis       Date:  2007-09       Impact factor: 6.883
  9 in total
  6 in total

1.  Clostridium difficile in the Long-Term Care Facility: Prevention and Management.

Authors:  Robin L P Jump; Curtis J Donskey
Journal:  Curr Geriatr Rep       Date:  2015-03

2.  Delirium and other clinical factors with Clostridium difficile infection that predict mortality in hospitalized patients.

Authors:  Laurie R Archbald-Pannone; Timothy L McMurry; Richard L Guerrant; Cirle A Warren
Journal:  Am J Infect Control       Date:  2015-04-24       Impact factor: 2.918

Review 3.  Clostridium Difficile Infection from a Surgical Perspective.

Authors:  Andreas M Kaiser; Rachel Hogen; Liliana Bordeianou; Karim Alavi; Paul E Wise; Ranjan Sudan
Journal:  J Gastrointest Surg       Date:  2015-04-28       Impact factor: 3.452

4.  Environmental transmission of Clostridioides difficile ribotype 027 at a long-term care facility; an outbreak investigation guided by whole genome sequencing.

Authors:  Bradley T Endres; Kierra M Dotson; Kelley Poblete; Jacob McPherson; Chris Lancaster; Eugénie Bassères; Ali Memariani; Sandi Arnold; Shawn Tupy; Conner Carlsen; Bonnie Morehead; Sophia Anyatonwu; Christa Cook; Khurshida Begum; M Jahangir Alam; Kevin W Garey
Journal:  Infect Control Hosp Epidemiol       Date:  2018-09-26       Impact factor: 3.254

5.  Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile.

Authors:  John P Hegarty; Jacek Krzeminski; Arun K Sharma; Diana Guzman-Villanueva; Volkmar Weissig; David B Stewart
Journal:  Int J Nanomedicine       Date:  2016-08-01

6.  Risk Factors for BI/NAP1/027 Clostridioides difficile Infections and Clinical Outcomes Compared With Non-NAP1 Strains.

Authors:  Nandita S Mani; John B Lynch; Ferric C Fang; Jeannie D Chan
Journal:  Open Forum Infect Dis       Date:  2019-10-12       Impact factor: 3.835
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.