Literature DB >> 25228225

A drug-perfluorocarbon nanoemulsion with an ultrathin silica coating for the synergistic effect of chemotherapy and ablation by high-intensity focused ultrasound.

Ming Ma1, Huixiong Xu, Hangrong Chen, Xiaoqing Jia, Kun Zhang, Qi Wang, Shuguang Zheng, Rong Wu, Minghua Yao, Xiaojun Cai, Faqi Li, Jianlin Shi.   

Abstract

The synergistic effect of chemotherapy and ablation using high-intensity focused ultrasound (HIFU) is realized with a newly developed drug-delivery system. The system comprises an ultrathin silica shell surrounding a poly(lactic-co-glycolic acid) nanoemulsion core containing the drug (CPT) and a perfluorocarbon (PFOB). This nanosystem presents many advantages in drug delivery, such as excellent structural stability, high drug-loading capacity, and rapid HIFU-mediated drug release.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  biomedical applications; composite materials; drug delivery; drug release; hybrid materials; silica

Mesh：

Substances：

Year:  2014        PMID： 25228225     DOI： 10.1002/adma.201402969

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  25 in total

1.  Phospholipid Capped Mesoporous Nanoparticles for Targeted High Intensity Focused Ultrasound Ablation.

Authors:  Adem Yildirim; Rajarshi Chattaraj; Nicholas T Blum; Dennis Shi; Kaushlendra Kumar; Andrew P Goodwin
Journal:  Adv Healthc Mater       Date:  2017-07-12       Impact factor: 9.933

2.  US/MR Bimodal Imaging-Guided Bio-Targeting Synergistic Agent for Tumor Therapy.

Authors:  Fujie Jiang; Lu Wang; Yu Tang; Yaotai Wang; Ningshan Li; Disen Wang; Zhong Zhang; Li Lin; Yan Du; Xia Ou; Jianzhong Zou
Journal:  Int J Nanomedicine       Date:  2022-07-04

3.  Small PLGA nanocapsules Co-encapsulating copper sulfide nanodots and fluorocarbon compound for photoacoustic imaging-guided HIFU synergistic therapy.

Authors:  Minghua Yao; Ming Ma; Huixiong Xu; Xiaoxia Pan; Guang Xu; Rong Wu
Journal:  RSC Adv       Date:  2018-01-24       Impact factor: 4.036

Review 4.  Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery: an update.

Authors:  Rafael R Castillo; Daniel Lozano; Blanca González; Miguel Manzano; Isabel Izquierdo-Barba; María Vallet-Regí
Journal:  Expert Opin Drug Deliv       Date:  2019-04-22       Impact factor: 6.648

5.  Ultrasound responsive mesoporous silica nanoparticles for biomedical applications.

Authors:  Miguel Manzano; María Vallet-Regí
Journal:  Chem Commun (Camb)       Date:  2019-02-28       Impact factor: 6.222

6.  Versatile Polymer Nanocapsules via Redox Competition.

Authors:  Jiajing Zhou; Ming Xu; Zhicheng Jin; Raina M Borum; Nicole Avakyan; Yong Cheng; Wonjun Yim; Tengyu He; Jingcheng Zhou; Zhuohong Wu; Yash Mantri; Jesse V Jokerst
Journal:  Angew Chem Int Ed Engl       Date:  2021-11-05       Impact factor: 15.336

7.  Comparison of the synergistic effect of lipid nanobubbles and SonoVue microbubbles for high intensity focused ultrasound thermal ablation of tumors.

Authors:  Yuanzhi Yao; Ke Yang; Yang Cao; Xuan Zhou; Jinshun Xu; Jianxin Liu; Qi Wang; Zhigang Wang; Dong Wang
Journal:  PeerJ       Date:  2016-02-22       Impact factor: 2.984

8.  Mesoporous composite nanoparticles for dual-modality ultrasound/magnetic resonance imaging and synergistic chemo-/thermotherapy against deep tumors.

Authors:  Nan Zhang; Ronghui Wang; Junnian Hao; Yang Yang; Hongmi Zou; Zhigang Wang
Journal:  Int J Nanomedicine       Date:  2017-10-05

Review 9.  Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery.

Authors:  Vera Paefgen; Dennis Doleschel; Fabian Kiessling
Journal:  Front Pharmacol       Date:  2015-09-15       Impact factor: 5.810

Review 10.  Targeted Nanotheranostics for Future Personalized Medicine: Recent Progress in Cancer Therapy.

Authors:  Sung Duk Jo; Sook Hee Ku; You-Yeon Won; Sun Hwa Kim; Ick Chan Kwon
Journal:  Theranostics       Date:  2016-06-15       Impact factor: 11.556
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