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Literature DB >> 25227948

A highly versatile convergent/divergent "onion peel" synthetic strategy toward potent multivalent glycodendrimers.

Rishi Sharma¹, Naresh Kottari, Yoann M Chabre, Leïla Abbassi, Tze Chieh Shiao, René Roy.

Abstract

Both convergent and divergent strategies for the synthesis of "onion peel" glycodendrimers are reported which resulted in one of the best multivalent ligands known against the virulent factor from a bacterial lectin isolated from Pseudomonas aeruginosa.

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Year: 2014 PMID： 25227948 DOI： 10.1039/c4cc06191h

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

8 in total

1. Subconjunctival injectable dendrimer-dexamethasone gel for the treatment of corneal inflammation.

Authors: Uri Soiberman; Siva P Kambhampati; Tony Wu; Manoj K Mishra; Yumin Oh; Rishi Sharma; Jiangxia Wang; Abdul Elah Al Towerki; Samuel Yiu; Walter J Stark; Rangaramanujam M Kannan
Journal: Biomaterials Date: 2017-02-16 Impact factor: 12.479

2. Janus second-order nonlinear optical dendrimers: their controllable molecular topology and corresponding largely enhanced performance.

Authors: Runli Tang; Shengmin Zhou; Ziyao Cheng; Gui Yu; Qian Peng; Huiyi Zeng; Guocong Guo; Qianqian Li; Zhen Li
Journal: Chem Sci Date: 2016-08-17 Impact factor: 9.825

3. Effect of Dendrimer Generation and Aglyconic Linkers on the Binding Properties of Mannosylated Dendrimers Prepared by a Combined Convergent and Onion Peel Approach.

Authors: Celia Sehad; Tze Chieh Shiao; Lamyaa M Sallam; Abdelkrim Azzouz; René Roy
Journal: Molecules Date: 2018-07-28 Impact factor: 4.411

A highly versatile convergent/divergent "onion peel" synthetic strategy toward potent multivalent glycodendrimers.

1. Subconjunctival injectable dendrimer-dexamethasone gel for the treatment of corneal inflammation.

2. Janus second-order nonlinear optical dendrimers: their controllable molecular topology and corresponding largely enhanced performance.

3. Effect of Dendrimer Generation and Aglyconic Linkers on the Binding Properties of Mannosylated Dendrimers Prepared by a Combined Convergent and Onion Peel Approach.

4. Targeting Mitochondrial Dysfunction and Oxidative Stress in Activated Microglia using Dendrimer-Based Therapeutics.

5. Scalable synthesis and validation of PAMAM dendrimer-N-acetyl cysteine conjugate for potential translation.

6. Dense hydroxyl polyethylene glycol dendrimer targets activated glia in multiple CNS disorders.

7. Glycosylation of PAMAM dendrimers significantly improves tumor macrophage targeting and specificity in glioblastoma.

Review 8. Microfluidics Technology for the Design and Formulation of Nanomedicines.