Literature DB >> 25226372

Characterizing the active opening of the eustachian tube in a hypobaric/hyperbaric pressure chamber.

Stefanie Mikolajczak1, Moritz Friedo Meyer, Moritz Hahn, Christine Korthäuer, Masen Dirk Jumah, Karl-Bernd Hüttenbrink, Maria Grosheva, Jan Christoffer Luers, Dirk Beutner.   

Abstract

OBJECTIVE: Active and passive opening of the Eustachian tube (ET) enables direct aeration of the middle ear and a pressure balance between middle ear and the ambient pressure. The aim of this study was to characterize standard values for the opening pressure (ETOP), the opening frequency (ETOF), and the opening duration (ETOD) for active tubal openings (Valsalva maneuver, swallowing) in healthy participants. DESIGN/PARTICIPANTS: In a hypobaric/hyperbaric pressure chamber, 30 healthy participants (19 women, 11 men; mean age, 25.57 ± 3.33 years) were exposed to a standardized profile of compression and decompression. The pressure values were recorded via continuous impedance measurement during the Valsalva maneuver and swallowing. Based on the data, standard curves were identified and the ETOP, ETOD, and ETOF were determined.
RESULTS: Recurring patterns of the pressure curve during active tube opening for the Valsalva maneuver and for active swallowing were characterized. The mean value for the Valsalva maneuver for ETOP was 41.21 ± 17.38 mbar; for the ETOD, it was 2.65 ± 1.87 seconds. In the active pressure compensation by swallowing, the mean value for the ETOP was 29.91 ± 13.07 mbar; and for the ETOD, it was 0.82 ± 0.53 seconds.
CONCLUSION: Standard values for the opening pressure of the tube and the tube opening duration for active tubal openings (Valsalva maneuver, swallowing) were described, and typical curve gradients for healthy subjects could be shown. This is another step toward analyzing the function of the tube in compression and decompression.

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Mesh:

Year:  2015        PMID: 25226372     DOI: 10.1097/MAO.0000000000000575

Source DB:  PubMed          Journal:  Otol Neurotol        ISSN: 1531-7129            Impact factor:   2.311


  5 in total

Review 1.  [The pressure-equalizing function of the Eustachian tube : Evaluation in a hypo-/hyperbaric pressure chamber].

Authors:  S Jansen; M F Meyer; K-B Hüttenbrink; D Beutner
Journal:  HNO       Date:  2017-08       Impact factor: 1.284

2.  Analyzing eustachian tube function in patients with symptoms of chronical Eustachian tube dysfunction by pressure chamber measurements.

Authors:  Moritz F Meyer; Christine Korthäuer; Stefanie Jansen; Karl-Bernd Hüttenbrink; Dirk Beutner
Journal:  Eur Arch Otorhinolaryngol       Date:  2018-03-17       Impact factor: 2.503

3.  Middle ear barotrauma in diving.

Authors:  Oskari H Lindfors; Anne K Räisänen-Sokolowski; Jari Suvilehto; Saku T Sinkkonen
Journal:  Diving Hyperb Med       Date:  2021-03-31       Impact factor: 0.887

4.  Influence of 30 and 60 Min of Hypobaric Hypoxia in Simulated Altitude of 15,000 ft on Human Proteome Profile.

Authors:  Jan Schmitz; Lydia J Kolaparambil Varghese; Felix Liebold; Moritz Meyer; Lukas Nerlich; Clement Starck; Seamus Thierry; Stefanie Jansen; Jochen Hinkelbein
Journal:  Int J Mol Sci       Date:  2022-03-31       Impact factor: 5.923

5.  Thirty Minutes of Hypobaric Hypoxia Provokes Alterations of Immune Response, Haemostasis, and Metabolism Proteins in Human Serum.

Authors:  Jochen Hinkelbein; Stefanie Jansen; Ivan Iovino; Silvia Kruse; Moritz Meyer; Fabrizio Cirillo; Hendrik Drinhaus; Andreas Hohn; Corinna Klein; Edoardo De Robertis; Dirk Beutner
Journal:  Int J Mol Sci       Date:  2017-08-31       Impact factor: 5.923

  5 in total

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