| Literature DB >> 2522605 |
C B Saper1, K M Hurley, M M Moga, H R Holmes, S A Adams, K M Leahy, P Needleman.
Abstract
Brain natriuretic peptide (BNP) is a recently discovered neuropeptide, isolated from the porcine brain, that is highly homologous to atriopeptin (AP), the atrial natriuretic peptide. We used a set of highly selective antisera against the two peptides to map their differential distribution immunohistochemically in the rat central nervous system. BNP immunoreactivity has a distinct distribution, involving many central autonomic and endocrine control structures that contain little if any AP immunoreactivity. AP and BNP belong to a family of neuropeptides that may be important in central cardiovascular control.Entities:
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Year: 1989 PMID: 2522605 DOI: 10.1016/0304-3940(89)90238-3
Source DB: PubMed Journal: Neurosci Lett ISSN: 0304-3940 Impact factor: 3.046