Marianna Vitkova1, Zuzana Gdovinova2, Jaroslav Rosenberger3, Jarmila Szilasiova2, Iveta Nagyová3, Pavol Mikula3, Martina Krokavcova4, Johan W Groothoff5, Jitse P van Dijk6. 1. Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia; Graduate School Kosice Institute for Society and Health, Safarik University, Kosice, Slovakia. Electronic address: marianna.vitkova@gmail.com. 2. Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia. 3. Graduate School Kosice Institute for Society and Health, Safarik University, Kosice, Slovakia. 4. Graduate School Kosice Institute for Society and Health, Safarik University, Kosice, Slovakia; 1st Department of Psychiatry, Faculty of Medicine, Safarik University, Kosice, Slovakia. 5. Department of Community and Occupational Health, University Medical Center Groningen, University of Groningen, the Netherlands. 6. Graduate School Kosice Institute for Society and Health, Safarik University, Kosice, Slovakia; Department of Community and Occupational Health, University Medical Center Groningen, University of Groningen, the Netherlands.
Abstract
BACKGROUND: Sleep disturbance is a common symptom of multiple sclerosis (MS) and knowledge about factors that contribute to poor sleep quality is scarce. OBJECTIVE: The aim was to explore the differences in the prevalence and determinants of poor sleep quality in a sample of patients with MS with disease duration ≤ 5 years and >5 years. METHODS: We collected data from 152 consecutive patients with MS; 66 patients (78% women, averaged 37.35 ± 10.1 years) were in the group with disease duration ≤ 5 years and 86 patients (73.3% women, averaged 42.10 ± 9.4 years) in the group with disease duration >5 years. Patients filled out the Pittsburgh Sleep Quality Index, the Hospital Anxiety and Depression Scale, the Multidimensional Fatigue Inventory, one item of the Incapacity Status Scale regarding bladder problems and one item of the Short Form-36 regarding pain. Multiple linear regression was used to analyze the relationship between the study variables. RESULTS: The prevalence of poor sleep is significantly higher in patients with longer disease duration (34.8 vs. 51.2%). Anxiety, reduced motivation and mental fatigue (all p < 0.05) were associated with poor sleep quality in patients with disease duration ≤5 years, whereas pain (p < 0.01), depression and mental fatigue (both p < 0.05) were in patients with disease duration >5 years. CONCLUSION: Sleep problems are present in patients with MS with both short and long disease duration, but these problems are associated with different factors. These should be recognized and managed in addition to the treatment of sleep disorders.
BACKGROUND: Sleep disturbance is a common symptom of multiple sclerosis (MS) and knowledge about factors that contribute to poor sleep quality is scarce. OBJECTIVE: The aim was to explore the differences in the prevalence and determinants of poor sleep quality in a sample of patients with MS with disease duration ≤ 5 years and >5 years. METHODS: We collected data from 152 consecutive patients with MS; 66 patients (78% women, averaged 37.35 ± 10.1 years) were in the group with disease duration ≤ 5 years and 86 patients (73.3% women, averaged 42.10 ± 9.4 years) in the group with disease duration >5 years. Patients filled out the Pittsburgh Sleep Quality Index, the Hospital Anxiety and Depression Scale, the Multidimensional Fatigue Inventory, one item of the Incapacity Status Scale regarding bladder problems and one item of the Short Form-36 regarding pain. Multiple linear regression was used to analyze the relationship between the study variables. RESULTS: The prevalence of poor sleep is significantly higher in patients with longer disease duration (34.8 vs. 51.2%). Anxiety, reduced motivation and mental fatigue (all p < 0.05) were associated with poor sleep quality in patients with disease duration ≤5 years, whereas pain (p < 0.01), depression and mental fatigue (both p < 0.05) were in patients with disease duration >5 years. CONCLUSION: Sleep problems are present in patients with MS with both short and long disease duration, but these problems are associated with different factors. These should be recognized and managed in addition to the treatment of sleep disorders.
Authors: Marianna Vitkova; Jaroslav Rosenberger; Zuzana Gdovinova; Jarmila Szilasiova; Pavol Mikula; Johan W Groothoff; Sijmen A Reijneveld; Jitse P van Dijk Journal: Brain Behav Date: 2016-09-20 Impact factor: 2.708
Authors: Ana Jerković; Una Mikac; Meri Matijaca; Vana Košta; Ana Ćurković Katić; Krešimir Dolić; Igor Vujović; Joško Šoda; Zoran Đogaš; Sanda Pavelin; Maja Rogić Vidaković Journal: J Clin Med Date: 2022-04-05 Impact factor: 4.241
Authors: Aleksandra Kołtuniuk; Magdalena Kazimierska-Zając; Dominika Pogłódek; Justyna Chojdak-Łukasiewicz Journal: Int J Environ Res Public Health Date: 2022-03-10 Impact factor: 3.390