Literature DB >> 25224650

In vitro study to simulate the intracardiac magnetohydrodynamic effect.

Waltraud B Buchenberg1, Wolfgang Mader2,3, Georg Hoppe1, Ramona Lorenz1, Marius Menza1, Martin Büchert1, Jens Timmer2,3,4, Bernd Jung1,5.   

Abstract

PURPOSE: Blood flow causes induced voltages via the magnetohydrodynamic (MHD) effect distorting electrograms (EGMs) made during magnetic resonance imaging. To investigate the MHD effect in this context MHD voltages occurring inside the human heart were simulated in an in vitro model system inside a 1.5 T MR system.
METHODS: The model was developed to produce MHD signals similar to those produced by intracardiac flow and to acquire them using standard clinical equipment. Additionally, a new approach to estimate MHD distortions on intracardiac electrograms is proposed based on the analytical calculation of the MHD signal from MR phase contrast data.
RESULTS: The recorded MHD signals were similar in magnitude to intracardiac signals that would be measured by an electrogram of the left ventricle. The dependency of MHD signals on magnetic field strength and electrode separation was well reflected by an analytical model. MHD signals reconstructed from MR flow data were in excellent agreement with the MHD signal measured by clinical equipment.
CONCLUSION: The in vitro model allows investigation of MHD effects on intracardiac electrograms. A phase contrast MR scan was successfully applied to characterize and estimate the MHD distortion on intracardiac signals allowing correction of these effects.
© 2014 Wiley Periodicals, Inc.

Entities:  

Keywords:  electrophysiology; hemodynamics; in vitro model system; intracardiac electrograms; magnetohydrodynamic effect; phase contrast MRI

Mesh:

Year:  2014        PMID: 25224650     DOI: 10.1002/mrm.25456

Source DB:  PubMed          Journal:  Magn Reson Med        ISSN: 0740-3194            Impact factor:   4.668


  2 in total

1.  The Magnetohydrodynamic Effect and its Associated Material Designs for Biomedical Applications: A State-of-the-Art Review.

Authors:  T Stan Gregory; Rui Cheng; Guoyi Tang; Leidong Mao; Zion Tsz Ho Tse
Journal:  Adv Funct Mater       Date:  2016-02-24       Impact factor: 18.808

2.  Exploring magnetohydrodynamic voltage distributions in the human body: Preliminary results.

Authors:  T Stan Gregory; Jonathan R Murrow; John N Oshinski; Zion Tsz Ho Tse
Journal:  PLoS One       Date:  2019-03-06       Impact factor: 3.240

  2 in total

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