Literature DB >> 25224328

Retinal screening of patients with cystic fibrosis-related diabetes in Wales -- a real eye opener.

R Roberts1, L Speight2, J Lee2, L George2, R I Ketchell2, D Lau2, J Duckers2.   

Abstract

BACKGROUND: The National Screening Committee recommends annual retinal screening for all diabetic patients over the age of twelve years. Currently, patients on insulin therapy for Cystic Fibrosis-Related Diabetes Mellitus (CFRD) at the All Wales Adult Cystic Fibrosis Service, UK are invited for annual screening.
METHODS: Age, sex, FEV(1)%, BMI, HbA1c, duration of diabetes, duration of insulin therapy, presence of retinopathy and attendance at retinal screening in 2012 were examined for patients on insulin therapy for CFRD.
RESULTS: 67 of the 228 (29%) patients attending the CF centre were receiving insulin therapy. 24 of the 67 (36%) did not attend retinal screening in 2012. Of the 43 who had retinal scans, 18 (42%) had evidence of retinopathy. Patients with retinopathy had a higher mean HbA1c (p=0.04), mean duration of diabetes and mean duration on insulin (p<0.001).
CONCLUSIONS: Almost half of the patients screened had evidence of retinopathy but over a third of the patients with CFRD did not attend screening appointments. Improving patient uptake of retinal scans will become increasingly important in an ageing CF population.
Copyright © 2014 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cystic fibrosis; Cystic fibrosis-related diabetes mellitus; Retinopathy; Screening

Mesh:

Substances:

Year:  2014        PMID: 25224328     DOI: 10.1016/j.jcf.2014.07.014

Source DB:  PubMed          Journal:  J Cyst Fibros        ISSN: 1569-1993            Impact factor:   5.482


  1 in total

1.  Retinopathy and microalbuminuria are common microvascular complications in cystic fibrosis-related diabetes.

Authors:  Punith Kempegowda; Harbinder Sunsoa; Joht S Chandan; Lauren M Quinn; Prashant M Amrelia; Syed Noman Atta; Sidrah Amir; Yee Suh Teh; Sabba Chaudhry; Anne de Bray; Rifat Rashid; Joanna L Whitehouse; Edward F Nash; Ateeq Syed
Journal:  Ther Adv Endocrinol Metab       Date:  2020-10-21       Impact factor: 3.565

  1 in total

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