Literature DB >> 25223895

A DNA aptamer to c-Met inhibits cancer cell migration.

R Ueki1, S Sando.   

Abstract

The HGF/c-Met pathway is known to play a key role in cancer metastasis. CLN0003_SL1, a 50-mer DNA aptamer that binds to the c-Met protein, was found to inhibit HGF-induced c-Met activation. This aptamer could suppress cancer cell motility in vitro.

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Year:  2014        PMID： 25223895     DOI： 10.1039/c4cc06016d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  14 in total

1.  Selective recognition of c-MYC Pu22 G-quadruplex by a fluorescent probe.

Authors:  Qianqian Zhai; Chao Gao; Jieqin Ding; Yashu Zhang; Barira Islam; Wenxian Lan; Haitao Hou; Hua Deng; Jun Li; Zhe Hu; Hany I Mohamed; Shengzhen Xu; Chunyang Cao; Shozeb M Haider; Dengguo Wei
Journal:  Nucleic Acids Res       Date:  2019-03-18       Impact factor: 16.971

Review 2.  [Research advances in the role of aptamers in the diagnosis and targeted therapy of pediatric cancer].

Authors:  Yi-Bin Zhang; Yan-Peng Wang; Jing Liu
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2018-05

Review 3.  Met in urological cancers.

Authors:  Yasuyoshi Miyata; Akihiro Asai; Kensuke Mitsunari; Tomohiro Matsuo; Kojiro Ohba; Yasushi Mochizuki; Hideki Sakai
Journal:  Cancers (Basel)       Date:  2014-12-16       Impact factor: 6.639

4.  Aptamers Binding to c-Met Inhibiting Tumor Cell Migration.

Authors:  Birgit Piater; Achim Doerner; Ralf Guenther; Harald Kolmar; Bjoern Hock
Journal:  PLoS One       Date:  2015-12-11       Impact factor: 3.240

5.  A chemically unmodified agonistic DNA with growth factor functionality for in vivo therapeutic application.

Authors:  Ryosuke Ueki; Satoshi Uchida; Naoto Kanda; Naoki Yamada; Ayaka Ueki; Momoko Akiyama; Kazuko Toh; Horacio Cabral; Shinsuke Sando
Journal:  Sci Adv       Date:  2020-04-01       Impact factor: 14.136

Review 6.  Dimeric and Multimeric DNA Aptamers for Highly Effective Protein Recognition.

Authors:  Claudia Riccardi; Ettore Napolitano; Domenica Musumeci; Daniela Montesarchio
Journal:  Molecules       Date:  2020-11-10       Impact factor: 4.411

Review 7.  Natural-Based Hydrogels for Tissue Engineering Applications.

Authors:  Manuel Gomez-Florit; Alberto Pardo; Rui M A Domingues; Ana L Graça; Pedro S Babo; Rui L Reis; Manuela E Gomes
Journal:  Molecules       Date:  2020-12-11       Impact factor: 4.411

8.  DNA mimics of red fluorescent proteins (RFP) based on G-quadruplex-confined synthetic RFP chromophores.

Authors:  Guangfu Feng; Chao Luo; Haibo Yi; Lin Yuan; Bin Lin; Xingyu Luo; Xiaoxiao Hu; Honghui Wang; Chunyang Lei; Zhou Nie; Shouzhuo Yao
Journal:  Nucleic Acids Res       Date:  2017-10-13       Impact factor: 16.971

9.  Simultaneous Monitoring of Cell-surface Receptor and Tumor-targeted Photodynamic Therapy via TdT-initiated Poly-G-Quadruplexes.

Authors:  Tianhui Shi; Menglin Wang; Hao Li; Miao Wang; Xingyu Luo; Yan Huang; Hong-Hui Wang; Zhou Nie; Shouzhuo Yao
Journal:  Sci Rep       Date:  2018-04-03       Impact factor: 4.379

10.  Targeting c-met receptor tyrosine kinase by the DNA aptamer SL1 as a potential novel therapeutic option for myeloma.

Authors:  Yibin Zhang; Hongmei Gao; Weihua Zhou; Sunming Sun; Yayue Zeng; Hui Zhang; Long Liang; Xiaojuan Xiao; Jianhui Song; Mao Ye; Yujia Yang; Jingfeng Zhao; Zi Wang; Jing Liu
Journal:  J Cell Mol Med       Date:  2018-10-24       Impact factor: 5.310
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