Literature DB >> 25220495

In vitro and in vivo removal of oral Candida from the denture base.

Kiyotsugu Kawasaki1,2, Yoshiaki Kamikawa2, Kazumasa Sugihara2.   

Abstract

OBJECTIVES: To clarify the effectiveness of ultrasonic cleaning for removing Candida lodged in the denture base.
MATERIALS AND METHODS: In vitro - Specimens of acrylic resin for denture plates contaminated with Candida cells were ultrasonically cleaned for 30 min. Washings were sampled every 5 min and cultured to investigate residual contamination, measured as colony forming units/ml, and the surfaces of the specimens were subjected to low-vacuum scanning electron microscopy (LV-SEM). In vivo - A total of 24 maxillary denture bases were brushed for 2 min under running tap water, then ultrasonically cleaned for 30 min. The washings were sampled every 5 min and cultured to investigate residual contamination.
RESULTS: In vitro - Maximum removal was achieved during the first 5 min of cleaning, with the mean CFU/ml counts significantly declining over time. More than 85% of all Candida was removed within the first 15 min in specimens inoculated with phosphate-buffered saline suspensions of Candida albicans and Candida glabrata. LV-SEM revealed a decreased number of Candida on the surface of the specimens after 30 min of ultrasonic cleaning. In vivo - Maximum removal was achieved during the first 5 min of cleaning, then the mean CFU/ml count significantly declined during the first 10 min. Ultrasonic cleaning for 15 min removed 88.4% of Candida species from the denture base.
CONCLUSIONS: Ultrasonic cleaning is a reliable and simple method for removing Candida lodged in the denture base.
© 2014 John Wiley & Sons A/S and The Gerodontology Association. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Ultrasonic cleaning; colony forming unit; denture; oral Candida

Mesh:

Substances:

Year:  2014        PMID: 25220495     DOI: 10.1111/ger.12149

Source DB:  PubMed          Journal:  Gerodontology        ISSN: 0734-0664            Impact factor:   2.980


  3 in total

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Authors:  Krid Kamonkhantikul; Mansuang Arksornnukit; Hidekazu Takahashi
Journal:  Int J Nanomedicine       Date:  2017-03-27

2.  Efficacy of removing Candida albicans from orthodontic acrylic bases: an in vitro study.

Authors:  Abdul Razzak A Ghazal; Ghassan Idris; Mohammad Y Hajeer; Karam Alawer; Richard D Cannon
Journal:  BMC Oral Health       Date:  2019-05-02       Impact factor: 2.757

3.  Impact of Denture Cleaning Method and Overnight Storage Condition on Denture Biofilm Mass and Composition: A Cross-Over Randomized Clinical Trial.

Authors:  Joke Duyck; Katleen Vandamme; Stefanie Krausch-Hofmann; Lies Boon; Katrien De Keersmaecker; Eline Jalon; Wim Teughels
Journal:  PLoS One       Date:  2016-01-05       Impact factor: 3.240

  3 in total

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