Literature DB >> 25220437

Differential effects of NMDA receptor antagonism on spine density.

Rebecca M Ruddy1, Yuxiao Chen, Marija Milenkovic, Amy J Ramsey.   

Abstract

The authors demonstrate that different NMDAR antagonists (ketamine and MK-801) have varying effects on spine density depending on dose, drug regimen, and brain region. While acute ketamine treatment increases cortical spine density in mice, subchronic exposure to either drug reduces spine density in both the cortex and striatum.
© 2014 Wiley Periodicals, Inc.

Entities:  

Keywords:  MK-801; NMDA receptor; antidepressant; ketamine; spine density

Mesh：

Substances：

Year:  2014        PMID： 25220437      PMCID： PMC5700749          DOI： 10.1002/syn.21784

Source DB:  PubMed          Journal:  Synapse        ISSN： 0887-4476            Impact factor:   2.562


  33 in total

1.  Associative memory formation increases the observation of dendritic spines in the hippocampus.

Authors:  Benedetta Leuner; Jacqueline Falduto; Tracey J Shors
Journal:  J Neurosci       Date:  2003-01-15       Impact factor: 6.167

2.  Regulation of spine morphology and spine density by NMDA receptor signaling in vivo.

Authors:  Sila K Ultanir; Ji-Eun Kim; Benjamin J Hall; Thomas Deerinck; Mark Ellisman; Anirvan Ghosh
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-28       Impact factor: 11.205

3.  Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning.

Authors:  Jonathan L Brigman; Tara Wright; Giuseppe Talani; Shweta Prasad-Mulcare; Seiichiro Jinde; Gail K Seabold; Poonam Mathur; Margaret I Davis; Roland Bock; Richard M Gustin; Roger J Colbran; Veronica A Alvarez; Kazu Nakazawa; Eric Delpire; David M Lovinger; Andrew Holmes
Journal:  J Neurosci       Date:  2010-03-31       Impact factor: 6.167

4.  Egocentric working memory impairment and dendritic spine plastic changes in prefrontal neurons after NMDA receptor blockade in rats.

Authors:  Dulce A Velázquez-Zamora; Myrna M González-Ramírez; Carlos Beas-Zárate; Ignacio González-Burgos
Journal:  Brain Res       Date:  2011-06-15       Impact factor: 3.252

5.  Stably maintained dendritic spines are associated with lifelong memories.

Authors:  Guang Yang; Feng Pan; Wen-Biao Gan
Journal:  Nature       Date:  2009-11-29       Impact factor: 49.962

6.  Olfactory learning is associated with increased spine density along apical dendrites of pyramidal neurons in the rat piriform cortex.

Authors:  S Knafo; Y Grossman; E Barkai; G Benshalom
Journal:  Eur J Neurosci       Date:  2001-02       Impact factor: 3.386

7.  Contrasting effects of motor and visual spatial learning tasks on dendritic arborization and spine density in rats.

Authors:  Bryan Kolb; Jan Cioe; Wendy Comeau
Journal:  Neurobiol Learn Mem       Date:  2008-06-10       Impact factor: 2.877

8.  Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation.

Authors:  Adam C Roberts; Javier Díez-García; Ramona M Rodriguiz; Iciar Paula López; Rafael Luján; Rebeca Martínez-Turrillas; Esther Picó; Maile A Henson; Danilo R Bernardo; Thomas M Jarrett; Dallis J Clendeninn; Laura López-Mascaraque; Guoping Feng; Donald C Lo; John F Wesseling; William C Wetsel; Benjamin D Philpot; Isabel Pérez-Otaño
Journal:  Neuron       Date:  2009-08-13       Impact factor: 17.173

9.  Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.

Authors:  Sungho Maeng; Carlos A Zarate; Jing Du; Robert J Schloesser; Joseph McCammon; Guang Chen; Husseini K Manji
Journal:  Biol Psychiatry       Date:  2007-07-23       Impact factor: 13.382

10.  Diolistic labeling of neuronal cultures and intact tissue using a hand-held gene gun.

Authors:  John A O'Brien; Sarah C R Lummis
Journal:  Nat Protoc       Date:  2006       Impact factor: 13.491
View more
  10 in total

1.  mGluR5 Positive and Negative Allosteric Modulators Differentially Affect Dendritic Spine Density and Morphology in the Prefrontal Cortex.

Authors:  Amber L LaCrosse; Sara B Taylor; Natali E Nemirovsky; Justin T Gass; Michael F Olive
Journal:  CNS Neurol Disord Drug Targets       Date:  2015       Impact factor: 4.388

2.  S-Ketamine Reverses Hippocampal Dendritic Spine Deficits in Flinders Sensitive Line Rats Within 1 h of Administration.

Authors:  Giulia Treccani; Maryam Ardalan; Fenghua Chen; Laura Musazzi; Maurizio Popoli; Gregers Wegener; Jens Randel Nyengaard; Heidi Kaastrup Müller
Journal:  Mol Neurobiol       Date:  2019-04-29       Impact factor: 5.590

3.  Alcohol Triggers Reemergence of Ketamine-Like Experience in a Ketamine Ex-User.

Authors:  Fong Chang; Ke Xu; Ming-Chyi Huang; John H Krystal
Journal:  J Clin Psychopharmacol       Date:  2017-02       Impact factor: 3.153

Review 4.  Dendritic Spine Elimination: Molecular Mechanisms and Implications.

Authors:  Ivar S Stein; Karen Zito
Journal:  Neuroscientist       Date:  2018-05-02       Impact factor: 7.519

Review 5.  Sex differences in resilience: Experiential factors and their mechanisms.

Authors:  Isabella P Fallon; Margaret K Tanner; Benjamin N Greenwood; Michael V Baratta
Journal:  Eur J Neurosci       Date:  2019-12-20       Impact factor: 3.386

6.  Environmental enrichment or selective activation of parvalbumin-expressing interneurons ameliorates synaptic and behavioral deficits in animal models with schizophrenia-like behaviors during adolescence.

Authors:  Yuhua Huang; Hehai Jiang; Qiyu Zheng; Albert Hiu Ka Fok; Xiaoyang Li; C Geoffrey Lau; Cora Sau Wan Lai
Journal:  Mol Psychiatry       Date:  2021-01-20       Impact factor: 13.437

Review 7.  Can pharmacotherapy improve treatment outcomes in people with co-occurring major depressive and cocaine use disorders?

Authors:  Gustavo A Angarita; Hasti Hadizadeh; Ignacio Cerdena; Marc N Potenza
Journal:  Expert Opin Pharmacother       Date:  2021-06-23       Impact factor: 4.103

8.  Longitudinal Effects of Ketamine on Dendritic Architecture In Vivo in the Mouse Medial Frontal Cortex.

Authors:  Victoria Phoumthipphavong; Florent Barthas; Samantha Hassett; Alex C Kwan
Journal:  eNeuro       Date:  2016-04-04

9.  Longitudinal two-photon imaging in somatosensory cortex of behaving mice reveals dendritic spine formation enhancement by subchronic administration of low-dose ketamine.

Authors:  Evgeny Pryazhnikov; Ekaterina Mugantseva; Plinio Casarotto; Julia Kolikova; Senem Merve Fred; Dmytro Toptunov; Ramil Afzalov; Pirta Hotulainen; Vootele Voikar; Ryan Terry-Lorenzo; Sharon Engel; Sergei Kirov; Eero Castren; Leonard Khiroug
Journal:  Sci Rep       Date:  2018-04-24       Impact factor: 4.379

10.  Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice.

Authors:  Yuxiao Chen; Marija Milenkovic; Wendy Horsfall; Ali Salahpour; Scott H Soderling; Amy J Ramsey
Journal:  PLoS One       Date:  2018-10-23       Impact factor: 3.240
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.