Literature DB >> 2521923

Transcription activation by the adenovirus E1a protein.

J W Lillie1, M R Green.   

Abstract

The adenovirus E1a protein stimulates transcription of a wide variety of viral and cellular genes. It is shown here that E1a has the two functions characteristic of a typical cellular activator: one direct E1a to the promoter, perhaps by interacting with a DNA-bound protein, and the other, an activating region, enables the bound activator to stimulate transcription.

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Year:  1989        PMID： 2521923     DOI： 10.1038/338039a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  311 in total

1.  Activation of cJUN N-terminal kinase by herpes simplex virus type 1 enhances viral replication.

Authors:  T I McLean; S L Bachenheimer
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

2.  Chromatin remodeling and activation of chromosomal DNA replication by an acidic transcriptional activation domain from BRCA1.

Authors:  Y F Hu; Z L Hao; R Li
Journal:  Genes Dev       Date:  1999-03-15       Impact factor: 11.361

3.  Corepressor required for adenovirus E1B 55,000-molecular-weight protein repression of basal transcription.

Authors:  M E Martin; A J Berk
Journal:  Mol Cell Biol       Date:  1999-05       Impact factor: 4.272

4.  Target selectivity of bicoid is dependent on nonconsensus site recognition and protein-protein interaction.

Authors:  C Zhao; V Dave; F Yang; T Scarborough; J Ma
Journal:  Mol Cell Biol       Date:  2000-11       Impact factor: 4.272

5.  Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes.

Authors:  Heather L Wiegand; Glen A Coburn; Yan Zeng; Yibin Kang; Hal P Bogerd; Bryan R Cullen
Journal:  Mol Cell Biol       Date:  2002-01       Impact factor: 4.272

6.  Expression and purification of recombinant human c-Fos/c-Jun that is highly active in DNA binding and transcriptional activation in vitro.

Authors:  H A Ferguson; J A Goodrich
Journal:  Nucleic Acids Res       Date:  2001-10-15       Impact factor: 16.971

7.  The murine Sim-2 gene product inhibits transcription by active repression and functional interference.

Authors:  P Moffett; M Reece; J Pelletier
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

8.  An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

Authors:  G J Kato; J Barrett; M Villa-Garcia; C V Dang
Journal:  Mol Cell Biol       Date:  1990-11       Impact factor: 4.272

9.  Multiple positive and negative regulatory elements in the promoter of the mouse homeobox gene Hoxb-4.

Authors:  A Gutman; J Gilthorpe; P W Rigby
Journal:  Mol Cell Biol       Date:  1994-12       Impact factor: 4.272

10.  Complementary functions of E1a conserved region 1 cooperate with conserved region 3 to activate adenovirus serotype 5 early promoters.

Authors:  H K Wong; E B Ziff
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103
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