Yanfei Chen1, Gang Song1, Liqun Jiao2, Yabing Wang1, Yan Ma1, Feng Ling1. 1. Department of Neurosurgery, Xuan Wu Hospital, Capital Medical University, Beijing 10053, China. 2. Department of Neurosurgery, Xuan Wu Hospital, Capital Medical University, Beijing 10053, China. Electronic address: jiaoliqun@gmail.com.
Abstract
OBJECTIVE: This retrospective study aimed to evaluate our initial experience with carotid endarterectomy in a Chinese population. METHODS: Four hundred and thirty-three patients who underwent carotid endarterectomies at Xuan Wu Hospital Capital Medical University between January 1, 2001, and December 31, 2012, were reviewed. The postoperative 30-day complications were analyzed. Univariate and multivariate logistic regression analyses were used to analyze the factors associated with perioperative stroke and death. RESULTS: The overall 30-day complication rates after surgery were 4.08% for death and stroke, 3.63% for cranial nerve injuries, and 3.63% for heart complications. The mean follow-up time was 32.99 months, and only 11 cases required restenosis, including two that were symptomatic (experiencing transient ischemic attacks). In the univariate analysis, a history of cerebral infarction was present preoperatively in 179 patients, of whom 12 (6.70%) had a postoperative stroke or died (P=0.021). Thirty-two patients had a modified Ranking score (mRS)≥ 3, and six (18.75%) of these patients had a postoperative stroke or died (P<0.001). In the multivariate logistic regression, female gender (OR: 4.669; 95% CI: 1.238-17.602; P=0.023), current smoking habits (OR: 3.826; 95% CI: 1.298-11.277; P=0.015), and an mRS ≥ 3 (OR: 1.540; 95% CI: 3.844-40.909; P<0.001) were independent risk factors for perioperative stroke and death. CONCLUSIONS: In our single-center study, carotid endarterectomies appeared to effectively prevent and treat the carotid artery stenosis that leads to stroke. Female gender, current smoking habits, and neurological deficits (mRS ≥ 3) increased the perioperative stroke and death rates.
OBJECTIVE: This retrospective study aimed to evaluate our initial experience with carotid endarterectomy in a Chinese population. METHODS: Four hundred and thirty-three patients who underwent carotid endarterectomies at Xuan Wu Hospital Capital Medical University between January 1, 2001, and December 31, 2012, were reviewed. The postoperative 30-day complications were analyzed. Univariate and multivariate logistic regression analyses were used to analyze the factors associated with perioperative stroke and death. RESULTS: The overall 30-day complication rates after surgery were 4.08% for death and stroke, 3.63% for cranial nerve injuries, and 3.63% for heart complications. The mean follow-up time was 32.99 months, and only 11 cases required restenosis, including two that were symptomatic (experiencing transient ischemic attacks). In the univariate analysis, a history of cerebral infarction was present preoperatively in 179 patients, of whom 12 (6.70%) had a postoperative stroke or died (P=0.021). Thirty-two patients had a modified Ranking score (mRS)≥ 3, and six (18.75%) of these patients had a postoperative stroke or died (P<0.001). In the multivariate logistic regression, female gender (OR: 4.669; 95% CI: 1.238-17.602; P=0.023), current smoking habits (OR: 3.826; 95% CI: 1.298-11.277; P=0.015), and an mRS ≥ 3 (OR: 1.540; 95% CI: 3.844-40.909; P<0.001) were independent risk factors for perioperative stroke and death. CONCLUSIONS: In our single-center study, carotid endarterectomies appeared to effectively prevent and treat the carotid artery stenosis that leads to stroke. Female gender, current smoking habits, and neurological deficits (mRS ≥ 3) increased the perioperative stroke and death rates.
Authors: Jian Wang; Weici Wang; Bi Jin; Yanrong Zhang; Ping Xu; Feixiang Xiang; Yi Zheng; Juan Chen; Shi Sheng; Chenxi Ouyang; Yiqing Li Journal: Biomed Res Int Date: 2016-08-23 Impact factor: 3.411
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