Mahmoud Jabbarvand1, Hesam Hashemian2, Mehdi Khodaparast1, Hadi Ghadimi1, Elias Khalilipour1. 1. From the Department of Ophthalmology, Ophthalmology Research Center, Tehran University of Medical Sciences, Farabi Eye Hospital, Tehran, Iran. 2. From the Department of Ophthalmology, Ophthalmology Research Center, Tehran University of Medical Sciences, Farabi Eye Hospital, Tehran, Iran. Electronic address: shhlucky@yahoo.com.
Abstract
PURPOSE: To evaluate the visual and refractive outcomes, endothelial cell count (ECC), ocular surface changes, corneal aberrations, and biomechanical profile changes after femtosecond laser-assisted anterior lamellar keratoplasty surgery for superficial corneal scars. SETTING: Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran. DESIGN: Prospective case series. METHODS: Patients with superficial corneal scars had femtosecond laser-assisted anterior lamellar keratoplasty. Visual and refractive results, ECC, ocular surface changes, corneal aberrations, and biomechanical profiles were assessed preoperatively and for 1 year postoperatively. RESULTS: Nineteen eyes (19 patients) were evaluated. A significant decline occurred in refractive astigmatism and corneal astigmatism after 1 year. There was a nonsignificant reduction in corneal hysteresis and the corneal resistance factor from preoperatively to 1 year postoperatively. The corneal-compensated intraocular pressure (IOP) and Goldmann-correlated IOP increased during the follow-up; the increase was not significant. A statistically insignificant reduction in the root mean square for trefoil and spherical aberrations occurred between 1 month and 1 year postoperatively (P=.1 and P=.4, respectively). The decreases in primary coma and total higher-order aberrations approached significance (P=.08 and P=.07, respectively). There were no significant changes in the central corneal thickness, ECC, or ocular surface parameters. No intraoperative complications occurred. CONCLUSION: Femtosecond laser-assisted anterior lamellar keratoplasty was an efficient and safe procedure for improving the quality of vision in patients with anterior corneal pathology, and the results remained stable during the 1-year follow-up. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
PURPOSE: To evaluate the visual and refractive outcomes, endothelial cell count (ECC), ocular surface changes, corneal aberrations, and biomechanical profile changes after femtosecond laser-assisted anterior lamellar keratoplasty surgery for superficial corneal scars. SETTING: Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran. DESIGN: Prospective case series. METHODS:Patients with superficial corneal scars had femtosecond laser-assisted anterior lamellar keratoplasty. Visual and refractive results, ECC, ocular surface changes, corneal aberrations, and biomechanical profiles were assessed preoperatively and for 1 year postoperatively. RESULTS: Nineteen eyes (19 patients) were evaluated. A significant decline occurred in refractive astigmatism and corneal astigmatism after 1 year. There was a nonsignificant reduction in corneal hysteresis and the corneal resistance factor from preoperatively to 1 year postoperatively. The corneal-compensated intraocular pressure (IOP) and Goldmann-correlated IOP increased during the follow-up; the increase was not significant. A statistically insignificant reduction in the root mean square for trefoil and spherical aberrations occurred between 1 month and 1 year postoperatively (P=.1 and P=.4, respectively). The decreases in primary coma and total higher-order aberrations approached significance (P=.08 and P=.07, respectively). There were no significant changes in the central corneal thickness, ECC, or ocular surface parameters. No intraoperative complications occurred. CONCLUSION: Femtosecond laser-assisted anterior lamellar keratoplasty was an efficient and safe procedure for improving the quality of vision in patients with anterior corneal pathology, and the results remained stable during the 1-year follow-up. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
Authors: Wei Zhong; Mario Montana; Samuel M Santosa; Irene D Isjwara; Yu-Hui Huang; Kyu-Yeon Han; Christopher O'Neil; Ashley Wang; Maria Soledad Cortina; Jose de la Cruz; Qiang Zhou; Mark I Rosenblatt; Jin-Hong Chang; Dimitri T Azar Journal: Surv Ophthalmol Date: 2017-12-27 Impact factor: 6.048