Literature DB >> 25218305

Targeting the transforming growth factor (TGF)-β cascade in the remodeling heart: benefits and perils.

Nikolaos G Frangogiannis1.   

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Year:  2014        PMID： 25218305      PMCID： PMC4408532          DOI： 10.1016/j.yjmcc.2014.09.001

Source DB:  PubMed          Journal:  J Mol Cell Cardiol        ISSN： 0022-2828            Impact factor:   5.000


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  26 in total

Review 1.  Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation.

Authors:  Andrew Leask
Journal:  Circ Res       Date:  2010-06-11       Impact factor: 17.367

2.  CD4+ T cells promote the transition from hypertrophy to heart failure during chronic pressure overload.

Authors:  Fanny Laroumanie; Victorine Douin-Echinard; Joffrey Pozzo; Olivier Lairez; Florence Tortosa; Claire Vinel; Christine Delage; Denis Calise; Marianne Dutaur; Angelo Parini; Nathalie Pizzinat
Journal:  Circulation       Date:  2014-03-21       Impact factor: 29.690

3.  Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction.

Authors:  Marcin Dobaczewski; Marcin Bujak; Na Li; Carlos Gonzalez-Quesada; Leonardo H Mendoza; Xiao-Fan Wang; Nikolaos G Frangogiannis
Journal:  Circ Res       Date:  2010-06-03       Impact factor: 17.367

Review 4.  TGF-β signaling in fibrosis.

Authors:  Anna Biernacka; Marcin Dobaczewski; Nikolaos G Frangogiannis
Journal:  Growth Factors       Date:  2011-07-11       Impact factor: 2.511

5.  Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload.

Authors:  Norimichi Koitabashi; Thomas Danner; Ari L Zaiman; Yigal M Pinto; Janelle Rowell; Joseph Mankowski; Dou Zhang; Taishi Nakamura; Eiki Takimoto; David A Kass
Journal:  J Clin Invest       Date:  2011-05-02       Impact factor: 14.808

6.  Angiotensin II stimulates apoptosis via TGF-beta1 signaling in ventricular cardiomyocytes of rat.

Authors:  D Schröder; J Heger; H M Piper; G Euler
Journal:  J Mol Med (Berl)       Date:  2006-08-19       Impact factor: 4.599

7.  Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction.

Authors:  Sih Min Tan; Yuan Zhang; Kim A Connelly; Richard E Gilbert; Darren J Kelly
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-02-12       Impact factor: 4.733

8.  Endothelial-to-mesenchymal transition contributes to cardiac fibrosis.

Authors:  Elisabeth M Zeisberg; Oleg Tarnavski; Michael Zeisberg; Adam L Dorfman; Julie R McMullen; Erika Gustafsson; Anil Chandraker; Xueli Yuan; William T Pu; Anita B Roberts; Eric G Neilson; Mohamed H Sayegh; Seigo Izumo; Raghu Kalluri
Journal:  Nat Med       Date:  2007-07-29       Impact factor: 53.440

9.  Attenuated development of cardiac fibrosis in left ventricular pressure overload by SM16, an orally active inhibitor of ALK5.

Authors:  Kristin V T Engebretsen; Kristine Skårdal; Sigrid Bjørnstad; Henriette S Marstein; Biljana Skrbic; Ivar Sjaastad; Geir Christensen; Johannes L Bjørnstad; Theis Tønnessen
Journal:  J Mol Cell Cardiol       Date:  2014-08-26       Impact factor: 5.000

Review 10.  Transforming growth factor beta as a therapeutic target in systemic sclerosis.

Authors:  John Varga; Boris Pasche
Journal:  Nat Rev Rheumatol       Date:  2009-04       Impact factor: 20.543
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  11 in total

Review 1.  The role of transforming growth factor (TGF)-β in the infarcted myocardium.

Authors:  Nikolaos G Frangogiannis
Journal:  J Thorac Dis       Date:  2017-03       Impact factor: 2.895

Review 2.  Anti-inflammatory therapies in myocardial infarction: failures, hopes and challenges.

Authors:  Shuaibo Huang; Nikolaos G Frangogiannis
Journal:  Br J Pharmacol       Date:  2018-03-04       Impact factor: 8.739

3.  MerTK Cleavage on Resident Cardiac Macrophages Compromises Repair After Myocardial Ischemia Reperfusion Injury.

Authors:  Matthew DeBerge; Xin Yi Yeap; Shirley Dehn; Shuang Zhang; Lubov Grigoryeva; Sol Misener; Daniel Procissi; Xin Zhou; Daniel C Lee; William A Muller; Xunrong Luo; Carla Rothlin; Ira Tabas; Edward B Thorp
Journal:  Circ Res       Date:  2017-08-29       Impact factor: 17.367

Review 4.  Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities.

Authors:  Ilaria Russo; Nikolaos G Frangogiannis
Journal:  J Mol Cell Cardiol       Date:  2015-12-15       Impact factor: 5.000

Review 5.  Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges.

Authors:  Amit Saxena; Ilaria Russo; Nikolaos G Frangogiannis
Journal:  Transl Res       Date:  2015-07-17       Impact factor: 7.012

Review 6.  The role of Smad signaling cascades in cardiac fibrosis.

Authors:  Anis Hanna; Claudio Humeres; Nikolaos G Frangogiannis
Journal:  Cell Signal       Date:  2020-11-05       Impact factor: 4.315

7.  Ataxia-telangiectasia mutated kinase: a potential new target for suppressing inflammation in heart failure?

Authors:  Rakesh C Kukreja
Journal:  J Am Heart Assoc       Date:  2014-12       Impact factor: 5.501

Review 8.  Inflammatory responses and inflammation-associated diseases in organs.

Authors:  Linlin Chen; Huidan Deng; Hengmin Cui; Jing Fang; Zhicai Zuo; Junliang Deng; Yinglun Li; Xun Wang; Ling Zhao
Journal:  Oncotarget       Date:  2017-12-14

9.  Cardiomyocyte Inflammasome Signaling in Cardiomyopathies and Atrial Fibrillation: Mechanisms and Potential Therapeutic Implications.

Authors:  Gong Chen; Mihail G Chelu; Dobromir Dobrev; Na Li
Journal:  Front Physiol       Date:  2018-08-13       Impact factor: 4.566

10.  Cardiac Fibrosis in Proteotoxic Cardiac Disease is Dependent Upon Myofibroblast TGF -β Signaling.

Authors:  Bidur Bhandary; Qinghang Meng; Jeanne James; Hanna Osinska; James Gulick; Iñigo Valiente-Alandi; Michelle A Sargent; Md Shenuarin Bhuiyan; Burns C Blaxall; Jeffery D Molkentin; Jeffrey Robbins
Journal:  J Am Heart Assoc       Date:  2018-10-16       Impact factor: 5.501
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