Literature DB >> 25217552

A series of forensic toxicology and drug seizure cases involving illicit fentanyl alone and in combination with heroin, cocaine or heroin and cocaine.

Laureen J Marinetti1, Brooke J Ehlers2.   

Abstract

The Montgomery County Coroner's Office Toxicology Section and the Miami Valley Regional Crime Lab (MVRCL) Drug Chemistry Section have been receiving case work in drug seizures, death cases and human performance cases involving products marketed as heroin or as illicit fentanyl. Upon analysis by the Drug Chemistry Section, these products were found to contain various drug(s) including illicit fentanyl only, illicit fentanyl and heroin, illicit fentanyl and cocaine and illicit fentanyl, heroin and cocaine. Both the Chemistry and Toxicology Sections began seeing these combinations starting in late October 2013. The percentage of the combinations encountered by the MVRCL as well as the physical appearance of the product, and the results of presumptive screening tests will be discussed. The demographics of the users and the results of toxicology and autopsy findings on the decedents will also be discussed. According to regional drug task force undercover agents, there is evidence that some of the products are being sold as illicit fentanyl and not just as a heroin product. Also, there is no evidence to support that the fentanyl source is being diverted from pharmaceutical grade fentanyl. The chemistry section currently has over 109 confirmed cases, and the toxicology section currently has 81 confirmed drug deaths, 8 driving under the influence of drugs and 1 suicidal hanging. Both sections are continuing to see these cases at the present time.
© The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

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Year:  2014        PMID: 25217552     DOI: 10.1093/jat/bku086

Source DB:  PubMed          Journal:  J Anal Toxicol        ISSN: 0146-4760            Impact factor:   3.367


  18 in total

1.  Quantitation of Fentanyl Analogs in Dried Blood Spots by Flow-Through Desorption Coupled to Online Solid Phase Extraction Tandem Mass Spectrometry.

Authors:  Rebecca L Shaner; Nicholas D Schulze; Craig Seymour; Elizabeth I Hamelin; Jerry D Thomas; Rudolph C Johnson
Journal:  Anal Methods       Date:  2017-06-16       Impact factor: 2.896

2.  Separation and Detection of Trace Fentanyl from Complex Mixtures Using Gradient Elution Moving Boundary Electrophoresis.

Authors:  Shannon T Krauss; David Ross; Thomas P Forbes
Journal:  Anal Chem       Date:  2019-09-27       Impact factor: 6.986

3.  Opioid-Involved Overdose Among Male Afghanistan/Iraq-Era U.S. Military Veterans: A Multidimensional Perspective.

Authors:  Alex S Bennett; Luther Elliott; Andrew Golub; Brett Wolfson-Stofko; Honoria Guarino
Journal:  Subst Use Misuse       Date:  2017-06-16       Impact factor: 2.164

4.  Street fentanyl use: Experiences, preferences, and concordance between self-reports and urine toxicology.

Authors:  Raminta Daniulaityte; Robert R Carlson; Matthew P Juhascik; Kraig E Strayer; Ioana E Sizemore
Journal:  Int J Drug Policy       Date:  2019-05-27

5.  Fentanyl and fentanyl-analog involvement in drug-related deaths.

Authors:  Zheng Dai; Marie A Abate; Gordon S Smith; James C Kraner; Allen R Mock
Journal:  Drug Alcohol Depend       Date:  2019-01-09       Impact factor: 4.492

6.  Evaluation of a lateral flow immunoassay for the detection of the synthetic opioid fentanyl.

Authors:  Daniel J Angelini; Tracey D Biggs; Michele N Maughan; Michael G Feasel; Edward Sisco; Jennifer W Sekowski
Journal:  Forensic Sci Int       Date:  2019-04-26       Impact factor: 2.395

7.  The Rapid Escalation of Fentanyl in Illicit Drug Evidence in Allegheny County, Pennsylvania, 2010-2016.

Authors:  Kathleen E Creppage; Joshua Yohannan; Karl Williams; Jeanine M Buchanich; Thomas J Songer; Stephen R Wisniewski; Anthony Fabio
Journal:  Public Health Rep       Date:  2018-02-01       Impact factor: 2.792

8.  In vitro pharmacology of fentanyl analogs at the human mu opioid receptor and their spectroscopic analysis.

Authors:  Sherif H Hassanien; Jonathon R Bassman; Carmelita M Perrien Naccarato; Jack J Twarozynski; John R Traynor; Donna M Iula; Jessica P Anand
Journal:  Drug Test Anal       Date:  2020-06-11       Impact factor: 3.345

Review 9.  γ-Hydroxybutyric Acid: Pharmacokinetics, Pharmacodynamics, and Toxicology.

Authors:  Melanie A Felmlee; Bridget L Morse; Marilyn E Morris
Journal:  AAPS J       Date:  2021-01-08       Impact factor: 4.009

10.  Fentanyl depression of respiration: Comparison with heroin and morphine.

Authors:  Rob Hill; Rakulan Santhakumar; William Dewey; Eamonn Kelly; Graeme Henderson
Journal:  Br J Pharmacol       Date:  2019-12-23       Impact factor: 8.739

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