Literature DB >> 25217547

XLR-11 and UR-144 in Washington state and state of Alaska driving cases.

Asa Louis1, Brianna L Peterson2, Fiona J Couper2.   

Abstract

The case reports for 18 driving cases positive for the synthetic cannabinoid substances XLR-11 and/or UR-144 are discussed. Eleven of these cases had drug recognition expert evaluations performed. Slurred speech, lack of convergence and body and eyelid tremors were the most consistently noted interview characteristic. Pulse and blood pressure of the subjects were within the expected range. Most of the drivers contacted demonstrated poor driving; however, their performance on the standardized field sobriety tests yielded inconsistent diagnostic information. All cases were negative for other commonly detected drugs that affect the central nervous system, although one case was additionally positive for other synthetic cannabinoids. Of the studied cases, six were positive for only UR-144, whereas eight contained only XLR-11. Four cases were found to have both.
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Year:  2014        PMID: 25217547     DOI: 10.1093/jat/bku067

Source DB:  PubMed          Journal:  J Anal Toxicol        ISSN: 0146-4760            Impact factor:   3.367


  5 in total

1.  Stratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice Reveals Congruence between In Vivo and In Vitro Assays.

Authors:  T W Grim; A J Morales; M M Gonek; J L Wiley; B F Thomas; G W Endres; L J Sim-Selley; D E Selley; S S Negus; A H Lichtman
Journal:  J Pharmacol Exp Ther       Date:  2016-08-17       Impact factor: 4.030

2.  Vaping Synthetic Cannabinoids: A Novel Preclinical Model of E-Cigarette Use in Mice.

Authors:  Timothy W Lefever; Julie A Marusich; Brian F Thomas; Daniel G Barrus; Nicholas C Peiper; Richard C Kevin; Jenny L Wiley
Journal:  Subst Abuse       Date:  2017-04-07

3.  Effects of synthetic cannabinoids on psychomotor, sensory and cognitive functions relevant for safe driving.

Authors:  Vasco Orazietti; Giuseppe Basile; Raffaele Giorgetti; Arianna Giorgetti
Journal:  Front Psychiatry       Date:  2022-09-26       Impact factor: 5.435

Review 4.  Emerging drugs of abuse: current perspectives on synthetic cannabinoids.

Authors:  Danièle Debruyne; Reynald Le Boisselier
Journal:  Subst Abuse Rehabil       Date:  2015-10-20

5.  Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice.

Authors:  Cornelius Hess; Clara T Schoeder; Thanigaimalai Pillaiyar; Burkhard Madea; Christa E Müller
Journal:  Forensic Toxicol       Date:  2016-05-17       Impact factor: 4.096

  5 in total

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