Massimo Clerici1, Francesco Bartoli1, Daniele Carretta2, Cristina Crocamo1, Paul Bebbington3, Giuseppe Carrà3. 1. Department of Translational Medicine and Surgery, University of Milano Bicocca, Monza, Italy. 2. Department of Translational Medicine and Surgery, University of Milano Bicocca, Monza, Italy. Electronic address: d.carretta1@campus.unimib.it. 3. Division of Psychiatry, Faculty of Brain Sciences, University College London, London, UK.
Abstract
OBJECTIVE: This study aimed to explore the prevalence of cardiovascular disease (CVD) risk factors in people with severe mental illness (SMI), estimating its weight on related risks in Southern Europe, an area with distinct dietary traditions. People with SMI may be more likely than general population to have high prevalence of risk factors for CVDs, due to several reasons, including poor health behaviours and psychopharmacological medications. METHOD: A cross-sectional study has been conducted, comparing inpatients with and without SMI. Univariate and multivariate analyses and logistic regression models have been carried out, exploring the effect of SMI on the prevalence of CVD risk factors. RESULTS: Although obesity and hypertriglyceridemia were more prevalent among people with SMI, controlling for relevant confounders in multivariate analyses we could not detect any significant difference. CONCLUSIONS: People with SMI may not necessarily have higher CVD risk, as compared with general population. Mediterranean healthy dietary habits, universal health coverage, families providing strong support, all are possible explanations for our findings. Further research is needed, exploring different mechanisms, with more detailed biological and genetics measures.
OBJECTIVE: This study aimed to explore the prevalence of cardiovascular disease (CVD) risk factors in people with severe mental illness (SMI), estimating its weight on related risks in Southern Europe, an area with distinct dietary traditions. People with SMI may be more likely than general population to have high prevalence of risk factors for CVDs, due to several reasons, including poor health behaviours and psychopharmacological medications. METHOD: A cross-sectional study has been conducted, comparing inpatients with and without SMI. Univariate and multivariate analyses and logistic regression models have been carried out, exploring the effect of SMI on the prevalence of CVD risk factors. RESULTS: Although obesity and hypertriglyceridemia were more prevalent among people with SMI, controlling for relevant confounders in multivariate analyses we could not detect any significant difference. CONCLUSIONS:People with SMI may not necessarily have higher CVD risk, as compared with general population. Mediterranean healthy dietary habits, universal health coverage, families providing strong support, all are possible explanations for our findings. Further research is needed, exploring different mechanisms, with more detailed biological and genetics measures.
Authors: Quintí Foguet-Boreu; Maria Isabel Fernandez San Martin; Gemma Flores Mateo; Edurne Zabaleta Del Olmo; Luís Ayerbe García-Morzon; Maria Perez-Piñar López; Luis Miguel Martin-López; Javier Montes Hidalgo; Concepción Violán Journal: BMC Psychiatry Date: 2016-05-12 Impact factor: 3.630
Authors: Attilio Carraro; Erica Gobbi; Marco Solmi; Andrew Watkins; Philip B Ward; Simon Rosenbaum Journal: Brain Behav Date: 2019-12-25 Impact factor: 2.708